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M-015

Supelco

Methaqualone solution

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C16H14N2O
CAS Number:
72-44-6
Molecular Weight:
250.30
MDL number:
MFCD00057320
UNSPSC Code:
41116107
PubChem Substance ID:
329817730
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)

concentration

1 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

2-8°C

SMILES string

Cc1ccccc1N2C(C)=Nc3ccccc3C2=O

InChI

1S/C16H14N2O/c1-11-7-3-6-10-15(11)18-12(2)17-14-9-5-4-8-13(14)16(18)19/h3-10H,1-2H3

InChI key

JEYCTXHKTXCGPB-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

General description

Methaqualone is a sedative-hypnotic and a central nervous system depressant sold under the trade name Quaalude for treatment of insomnia. Methaqualone also has a history of abuse, known by street names such as Disco biscuits, Lemmons, and 714s. This certified solution standard is applicable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from urine drug testing to forensic analysis and clinical toxicology.

Application


  • Pharmacokinetic studies: The analysis of Methaqualone in pharmacokinetic research employs liquid chromatography/tandem mass spectrometry, crucial for understanding its metabolism and excretion patterns. Such studies are vital for developing safety profiles and therapeutic guidelines for sedative-hypnotics (Yun et al., 2007).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

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Antimalarials: shortages and searches.
Stanley Scheindlin
Molecular interventions, 5(5), 268-272 (2005-10-27)
Phenytoin intoxication induced by Mandrax (methaqualone).
Rajesh Verma et al.
Epilepsy research, 98(2-3), 281-282 (2011-10-25)
J Klimes et al.
Die Pharmazie, 51(9), 651-653 (1996-09-01)
A HPLC method for quantification of kebuzone and its metabolites in whole blood was developed. The compounds and the internal standard were isolated from blood by solid-phase extraction on a C-18 cartridge. A blood sample was to be hemolyzed before
F Benoist et al.
European journal of biochemistry, 240(3), 713-720 (1996-09-15)
The role of microsomal triacylglycerol transfer protein (MTP) in the secretion of apolipoprotein B-100 (apoB-100) has been studied using an inhibitor of MTP: 4'-bromo-3'-methylmetaqualone. In vitro, this compound inhibits trioleoylglycerol transfer between lipid vesicles mediated by MTP with an IC50
G McCarthy et al.
The Cochrane database of systematic reviews, (2)(2), CD004146-CD004146 (2005-04-23)
Methaqualone is a potent quinazoline, a class of sedative-hypnotics, that has a high potential for abuse. While the oral use of methaqualone (Quaalude, Mandrax) has waned in western countries since the mid-late 1980's, the practice of smoking methaqualone is a
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