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P8877

Sigma-Aldrich

D-(−)-3-Phosphoglyceric acid disodium salt

greener alternative

≥93% dry basis (enzymatic), powder

Sinónimos:

(−)-Disodium D-3-phosphoglycerate, D-Glycerate 3-phosphate disodium salt

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About This Item

Fórmula empírica (notación de Hill):
C3H5Na2O7P
Número de CAS:
80731-10-8
Peso molecular:
230.02
Beilstein:
3767836
Número MDL:
MFCD00069569
Código UNSPSC:
12352201
ID de la sustancia en PubChem:
24898988
NACRES:
NA.25

origen biológico

synthetic (inorganic)

Nivel de calidad

200

Ensayo

≥93% dry basis (enzymatic)

Formulario

powder

características de los productos alternativos más sostenibles

Atom Economy
Design for Energy Efficiency
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurezas

<14% water (NMR)

color

white

solubilidad

H2O: 50 mg/mL, clear, colorless to faintly yellow

trazas de catión

Na: 18-22% (dry basis)

categoría alternativa más sostenible

Re-engineered,

temp. de almacenamiento

−20°C

cadena SMILES

[Na+].[Na+].O[C@H](COP(O)([O-])=O)C([O-])=O

InChI

1S/C3H7O7P.2Na/c4-2(3(5)6)1-10-11(7,8)9;;/h2,4H,1H2,(H,5,6)(H2,7,8,9);;/q;2*+1/p-2/t2-;;/m1../s1

Clave InChI

RGCJWQYUZHTJBE-YBBRRFGFSA-L

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Aplicación

D-(-)-3-Phosphoglyceric acid disodium salt has been used in a study to assess the phosphorylation of glyceric acid in aqueous solution. It has also been used in a study to characterize a glutathione- and NAD-dependent arsenate reduction linked to glycolysis.

Acciones bioquímicas o fisiológicas

3-Phosphoglyceric acid is an intermediate in glycolysis. It also a precursor in the formation of serine.

Otras notas

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Pictogramas

Health hazardExclamation mark
GHS08,GHS07

Palabra de señalización

Warning

Frases de peligro

H315,H319,H335,H371

Clasificaciones de peligro

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 2 - STOT SE 3

Órganos de actuación

Eyes,Central nervous system, Respiratory system

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

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Certificados de análisis (COA)

Lot/Batch Number
0000399555
0000369134
0000356750
0000355373
0000356750

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Visite la Librería de documentos

Balázs Németi et al.
Toxicological sciences : an official journal of the Society of Toxicology, 85(2), 847-858 (2005-03-25)
Reduction of arsenate (AsV) to the more toxic arsenite (AsIII) is of high toxicological importance, yet in vivo relevant enzymes involved have not been identified. Purine nucleoside phosphorylase (PNP) is an efficient AsV reductase in vitro, but its role in
V Kolb et al.
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 26(1), 7-13 (1996-02-01)
The phosphorylation of glyceric acid is an interesting prebiotic reaction because it converts a simple, potentially prebiotic organic molecule into phosphate derivatives that are central to carbohydrate metabolism. We find that 0.05 M glyceric acid in the presence of 0.5
Jeremy M Foster et al.
PloS one, 5(10), e13576-e13576 (2010-12-29)
The glycolytic phosphoglycerate mutases exist as non-homologous isofunctional enzymes (NISE) having independent evolutionary origins and no similarity in primary sequence, 3D structure, or catalytic mechanism. Cofactor-dependent PGM (dPGM) requires 2,3-bisphosphoglycerate for activity; cofactor-independent PGM (iPGM) does not. The PGM profile
Junji Okuda et al.
PloS one, 8(8), e72173-e72173 (2013-08-21)
Heart failure is associated with changes in cardiac energy metabolism. Glucose metabolism in particular is thought to be important in the pathogenesis of heart failure. We examined the effects of persistent overexpression of phosphoglycerate mutase 2 (Pgam2), a glycolytic enzyme
Jeremy M Foster et al.
Parasitology research, 104(5), 1047-1052 (2008-12-02)
Phosphoglycerate mutases (PGM) interconvert 2- and 3-phosphoglycerate in the glycolytic and gluconeogenic pathways. A putative cofactor-independent phosphoglycerate mutase gene (iPGM) was identified in the genome sequence of the Wolbachia endosymbiont from the filarial nematode, Brugia malayi (wBm). Since iPGM has
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