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Merck

79470

Sigma-Aldrich

D(+)-2-Phosphoglyceric acid sodium salt hydrate

≥75% (calc. on dry substance, enzymatic)

Sinónimos:

D-Glycerate 2-phosphate sodium salt, Sodium D-2-phosphoglycerate hydrate

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About This Item

Fórmula empírica (notación de Hill):
C3H7O7P · xNa+ · yH2O
Número de CAS:
Peso molecular:
186.06 (anhydrous free acid basis)
Código UNSPSC:
12352204
ID de la sustancia en PubChem:
NACRES:
NA.26
Ensayo:
≥75% (calc. on dry substance, enzymatic)
Formulario:
powder

Nivel de calidad

Ensayo

≥75% (calc. on dry substance, enzymatic)

Formulario

powder

impurezas

≤1% Pi
≤35% water

temp. de almacenamiento

−20°C

cadena SMILES

O=C(O)[C@@H](CO)OP(O)(O)=O.C.C

Clave InChI

PXJAQZYAJDMQJH-YBBRRFGFSA-N

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Acciones bioquímicas o fisiológicas

Enantiomerically pure metabolite of glycolysis/gluconeogenesis and also substrate for a number of important enzymes in central metabolism like enolase and phosphoglycerate mutase.
The enzyme enolase is responsible for reversible conversion of 2-phosphoglycerate (2-PG) into phosphoenolpyruvate (PEP). Phosphoglycerate mutase causes reversible isomerization of 3-phosphoglycerate and 2-phosphoglycerate in glycolysis and gluconeogenesis.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Molecular characterization of phosphoglycerate mutase in archaea.
van der Oost J, et al.
FEMS Microbiology Letters, 212, 111-120 (2002)
Jin-Ha Lee et al.
FEMS microbiology letters, 259(2), 240-248 (2006-06-01)
Enolase on the surface of streptococci putatively facilitates pathogenic invasion of the host organisms. The related Leuconostoc mesenteroides 512FMCM is nonpathogenic, but it too has an extracellular enolase. Purified isolates of extracellular dextransucrase from cultures of L. mesenteroides contain minute
E Zhang et al.
Biochemistry, 36(41), 12526-12534 (1997-11-05)
Enolase, a glycolytic enzyme that catalyzes the dehydration of 2-phospho-d-glycerate (PGA) to form phosphoenolpyruvate (PEP), is a homodimer in all eukaryotes and many prokaryotes. Here, we report the crystal structure of a complex between yeast enolase and an equilibrium mixture
Shivangi Agarwal et al.
Biochimica et biophysica acta, 1784(7-8), 986-994 (2008-05-06)
alpha-enolase of Bacillus anthracis has recently been classified as an immunodominant antigen and a potent virulence factor determinant. alpha-enolase (2-phospho-d-glycerate hydrolase (EC 4.2.1.11), a key glycolytic metalloenzyme catalyzes the dehydration of d-(+)-2-phosphoglyceric acid to phosphoenolpyruvate. Interaction of surface bound alpha-enolase
T M Larsen et al.
Biochemistry, 35(14), 4349-4358 (1996-04-09)
The equilibrium mixture of yeast enolase with substrate, 2-phospho-D-glycerate (2-PGA), and product, phosphoenolpyruvate (P-enolpyruvate), has been crystallized from solutions of poly(ethylene glycol) (PEG) at pH 8.0. Crystals belong to the space group C2 and have unit cell dimensions a =

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