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D1925

Sigma-Aldrich

Demecolcine solution

10 μg/mL in HBSS, ACF Qualified, BioXtra

Sinónimos:

Colcemid™ solution, N-Deacetyl-N-methylcolchicine solution

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About This Item

Número de CAS:
477-30-5
MDL number:
MFCD00075459
UNSPSC Code:
12352207
PubChem Substance ID:
24893569
NACRES:
NA.75

sterility

sterile-filtered

product line

BioXtra

form

liquid

concentration

10 μg/mL in HBSS

technique(s)

cell culture | mammalian: suitable

storage temp.

2-8°C

SMILES string

CN[C@H]1CCc2cc(OC)c(OC)c(OC)c2C3=CC=C(OC)C(=O)C=C13

InChI

1S/C21H25NO5/c1-22-15-8-6-12-10-18(25-3)20(26-4)21(27-5)19(12)13-7-9-17(24-2)16(23)11-14(13)15/h7,9-11,15,22H,6,8H2,1-5H3/t15-/m0/s1

InChI key

NNJPGOLRFBJNIW-HNNXBMFYSA-N

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Application

Used for cell synchronization by arresting them at metaphase. Qualified for use in animal component free applications.

Legal Information

Colcemid is a trademark of Ciba-Geigy Corporation

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Dimitris Ioannou et al.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 17(4), 519-530 (2009-08-01)
In the field of nanotechnology, quantum dots (QDs) are a novel class of inorganic fluorochromes composed of nanometre-scale crystals made of a semiconductor material. Given the remarkable optical properties that they possess, they have been proposed as an ideal material
Ting-Yuan Tseng et al.
Molecules (Basel, Switzerland), 25(18) (2020-09-11)
Identification of the existence of G-quadruplex (G4) structure, from a specific G-rich sequence in cells, is critical to the studies of structural biology and drug development. Accumulating evidence supports the existence of G4 structure in vivo. Particularly, time-gated fluorescence lifetime
Vandana Relan et al.
PloS one, 8(3), e58132-e58132 (2013-03-22)
Malignant mesothelioma is an aggressive tumour of serosal surfaces most commonly pleura. Characterised cell lines represent a valuable tool to study the biology of mesothelioma. The aim of this study was to develop and biologically characterise six malignant mesothelioma cell
Peter Burkovics et al.
Nucleic acids research, 44(7), 3176-3189 (2016-01-23)
Successful and accurate completion of the replication of damage-containing DNA requires mainly recombination and RAD18-dependent DNA damage tolerance pathways. RAD18 governs at least two distinct mechanisms: translesion synthesis (TLS) and template switching (TS)-dependent pathways. Whereas TS is mainly error-free, TLS
Mathew J Thayer
BioEssays : news and reviews in molecular, cellular and developmental biology, 34(9), 760-770 (2012-06-19)
Recent studies indicate that mammalian chromosomes contain discrete cis-acting loci that control replication timing, mitotic condensation, and stability of entire chromosomes. Disruption of the large non-coding RNA gene ASAR6 results in late replication, an under-condensed appearance during mitosis, and structural
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