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Documentos

V-019

Supelco

Vitamina B12

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Sinónimos:

α-(5,6-Dimetilbencimidazolil)cianocobamida, CN-Cbl, Cianocob(III)alamina, Cianocobalamina

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About This Item

Fórmula empírica (notación de Hill):
C63H88CoN14O14P
Número de CAS:
68-19-9
Peso molecular:
1355.37
Beilstein/REAXYS Number:
4122889
EC Number:
200-659-6
UNSPSC Code:
41116107
PubChem Substance ID:
329828962
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing
clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

C/C(C1=N[C@]([C@]([C@H](CC(N)=O)[C@@]/2(C)CCC(NC[C@@H](OP([O-])(O[C@H]3[C@@H](O)[C@@H](N4C=[N]5C6=C4C=C(C)C(C)=C6)O[C@@H]3CO)=O)C)=O)([H])N([Co+]5C#N)C2=C(C)/C([C@@H](CCC(N)=O)C/7(C)C)=NC7=C/8)(C)[C@@](C)(CC(N)=O)[C@@H]1CCC(N)=O)=C9N=C8[C@@H](CCC(N)=O)[C@

InChI

1S/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;;+2/p-2/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57?,59-,60+,61+,62+;;/m1../s1

InChI key

RMRCNWBMXRMIRW-QJRSUKKJSA-L

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General description

Cyanocobalamin is the most common and widely-produced of the vitamin B12 analogs. Vitamin B12, important for proper neuronal function and formation of blood cellular components, is monitored directly in patient serum samples by LC-MS/MS.

Application

This certified solution standard is suitable for use as a starting material in the preparation of linearity standards, calibrators or controls in a variety of testing applications from diagnostic testing of vitamin B12 deficiency by LC-MS/MS to quality control testing of vitamin B12-based dietary supplements/fortified foods or pharmaceutical preparations.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Referencia del producto
Descripción
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V-080

Pyridoxine-13C3 (Vitamin B6-13C3) hydrochloride solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

F-087

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signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Supelco

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(−)-Riboflavin

Vitamina B12 pharmaceutical secondary standard, certified reference material

Supelco

PHR1234

Vitamina B12

Vitamina B12 British Pharmacopoeia (BP) Assay Standard

BP466

Vitamina B12

Millipore

Millipore

1.24592

Vitamin B₁₂

Methylcobalamin vitamin B12 analog

Sigma-Aldrich

M9756

Methylcobalamin

Hossein Khedmat et al.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 24(4), 759-763 (2013-07-03)
Helicobacter pylori (HP) is a common infection worldwide and has been associated with severe morbidity. The level of vitamin B 12 in HP-infected chronic kidney disease (CKD) patients is reported to be lower than in the general population. The present
Spinal injection therapy for low back pain.
J Bart Staal et al.
JAMA, 309(23), 2439-2440 (2013-05-18)
Reversible disconnection syndrome: an unusual presentation of vitamin B12 deficiency.
Rajesh Verma et al.
Neurology India, 61(2), 167-169 (2013-05-07)
Christine M Armour et al.
Pediatrics, 132(1), e257-e261 (2013-06-19)
A neonate, who was found to have an elevated C3/C2 ratio and minimally elevated propionylcarnitine on newborn screening, was subsequently identified as having the rare cblF inborn error of vitamin B12 (cobalamin) metabolism. This disorder is characterized by the retention
Sabina Lutz et al.
Journal of the American Animal Hospital Association, 49(3), 197-203 (2013-03-29)
Juvenile cobalamin deficiency is a rare disease in border collies and its diagnosis requires a high level of clinical suspicion. The goal of this study was to increase awareness of this disease by describing the clinical and laboratory findings in
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Protocolos

HPLC Analysis of Vitamins B1 B6 B12

HPLC Analysis of Vitamins B1, B6 and B12 using Ascentis® Express RP-Amide

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