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V-016

Supelco

Nicotinamide

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Sinónimos:

Nicotinamide, Vitamin B3, Niacinamide, Nicotinic acid amide, Pyridine-3-carboxylic acid amide, Vitamin PP

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About This Item

Fórmula empírica (notación de Hill):
C6H6N2O
Número de CAS:
98-92-0
Peso molecular:
122.12
Beilstein/REAXYS Number:
383619
EC Number:
200-659-6
MDL number:
MFCD00006395
UNSPSC Code:
41116107
PubChem Substance ID:
329828959
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

128-131 °C (lit.)

application(s)

clinical testing
clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

NC(=O)c1cccnc1

InChI

1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)

InChI key

DFPAKSUCGFBDDF-UHFFFAOYSA-N

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General description

Nicotinamide is also known as niacinamide or nicotinic acid amide. It is the water-soluble form of Vitamin B3 found in plant and animal foods and mostly used as a dietary supplement.

Application

This certified solution standard is suitable for a variety of testing applications including quality control testing by HPLC for pharmaceutical preparations or dietary supplements.
Nicotinamide may be used as an analytical reference standard for the determination of the analyte in energy drinks by planar chromatography-multiple detection with confirmation by electrospray ionization mass spectrometry and in pharmaceutical formulations, by UV-visible spectrophotometry and multivariate analysis.

Biochem/physiol Actions

Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Referencia del producto
Descripción
Precios

V-014

Tiamina hydrochloride, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

V-017

Nicotinic acid, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

V-019

Vitamina B12, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

V-052

Thiamine-13C3 (Vitamin B1-13C3) hydrochloride solution, 100 μg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant®

V-055

(-)-Riboflavin-13C4,15N2 (Vitamin B2-13C4,15N2) solution, 100 μg/mL (1% ammonium acetate in 50:50 methanol:water), certified reference material, ampule of 1 mL, Cerilliant®

V-067

(−)-Riboflavin, 100 μg/mL (1% ammonium acetate in 50:50 methanol:water), certified reference material, ampule of 1 mL, Cerilliant®

V-063

Pantothenic acid-13C3,15N hemicalcium salt solution, 100 μg/mL (90:10 Methanol:Water, (as free acid)), certified reference material, ampule of 1 mL, Cerilliant®

V-056

Riboflavin 5′-phosphate sodium salt solution, 100 μg/mL (50:50 Methanol:1% Ammonium Acetate in Water, (as free phosphate)), certified reference material, ampule of 1 mL

V-069

Pyridoxal 5′-phosphate solution, 500 μg/mL (80:20 Water:Acetonitrile), certified reference material, ampule of 1 mL, Cerilliant®

V-080

Pyridoxine-13C3 (Vitamin B6-13C3) hydrochloride solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

F-087

Folic acid solution, 1 mg/mL in methanol with 0.1N NaOH, certified reference material, ampule of 1 mL, Cerilliant®

F-088

Folic acid-13C5,15N solution, 100 μg/mL (Methanol with 0.1 N NaOH), certified reference material, ampule of 1 mL, Cerilliant®

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Simultaneous determination of riboflavin, pyridoxine, nicotinamide, caffeine and taurine in energy drinks by planar chromatography-multiple detection with confirmation by electrospray ionization mass spectrometry
Aranda M and Morlock G
Journal of Chromatography A, 1131(1-2), 253-260 (2006)
Robert J Motzer et al.
The Lancet. Oncology, 14(6), 552-562 (2013-04-20)
In a phase 3 trial comparing the efficacy and safety of axitinib versus sorafenib as second-line treatment for metastatic renal cell carcinoma, patients given axitinib had a longer progression-free survival (PFS). Here, we report overall survival and updated efficacy, quality
New options for second-line therapy of advanced renal cancer.
Axel Bex
The Lancet. Oncology, 14(6), 450-451 (2013-04-20)
Thomas J Herzog et al.
Gynecologic oncology, 130(1), 25-30 (2013-04-18)
Sorafenib, an oral multikinase inhibitor of the VEGFR/PDGFR/Raf/MEK/ERK pathway, has shown potential activity in patients with recurrent ovarian cancer (OC). One strategy to prolong disease control and survival in patients with OC is maintenance therapy after achieving a complete response.
Simultaneous determination and classification of riboflavin, thiamine, nicotinamide and pyridoxine in pharmaceutical formulations, by UV-visible spectrophotometry and multivariate analysis
Lopez-de-Alba LP, et al.
Journal of the Brazilian Chemical Society, 17(4), 715-722 (2006)
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