![(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl N-succinimidyl carbonate for Copper-free Click Chemistry](/deepweb/assets/sigmaaldrich/product/structures/969/022/d6776082-2f7a-47c7-bcd4-3830dac0fb7d/640/d6776082-2f7a-47c7-bcd4-3830dac0fb7d.png)
![N-[(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl]-1,8-diamino-3,6-dioxaoctane for Copper-free Click Chemistry](/deepweb/assets/sigmaaldrich/product/structures/294/853/c5e47d84-5aee-4797-aa24-604f291171cc/640/c5e47d84-5aee-4797-aa24-604f291171cc.png)
There is no published value for the extinction coefficient of this molecule.
764019
Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester
≥90%
Sinónimos:
DBCO-PEG4-NHS ester, DBCO-PEG4-SE, DBCO-PEG4-succinimidyl ester
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About This Item
Fórmula empírica (notación de Hill):
C34H39N3O10
Peso molecular:
649.69
Número MDL:
Código UNSPSC:
12352108
ID de la sustancia en PubChem:
NACRES:
NA.22
En este momento no podemos mostrarle ni los precios ni la disponibilidad
Productos recomendados
Nivel de calidad
Ensayo
≥90%
Formulario
paste
idoneidad de la reacción
reaction type: click chemistry
reagent type: linker
grupo funcional
NHS ester
temp. de almacenamiento
−20°C
cadena SMILES
O=C(CCC(NCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4
InChI
1S/C34H39N3O10/c38-30(11-12-31(39)36-25-28-7-2-1-5-26(28)9-10-27-6-3-4-8-29(27)36)35-16-18-44-20-22-46-24-23-45-21-19-43-17-15-34(42)47-37-32(40)13-14-33(37)41/h1-8H,11-25H2,(H,35,38)
Clave InChI
RRCXYKNJTKJNTD-UHFFFAOYSA-N
Aplicación
Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester may be used in the synthesis of a prostate-specific membrane antigen (PSMA)-targeted single photon emission computed tomography (SPECT) agent via copper-less click chemistry.[1]
Succinimidyl ester (NHS, amine reactive) functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into amine containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free click chemistry cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.
Applications Include:
Applications Include:
- Protein-peptide conjugates
- Antibody-enzyme or antibody-drug conjugates
- Protein or peptide-oligonucleotide conjugates
- Surface modification
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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Explore the principles and applications of click chemistry in drug discovery, highlighting efficient reactions that streamline the synthesis of bioactive compounds.
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Explore the principles and applications of click chemistry in drug discovery, highlighting efficient reactions that streamline the synthesis of bioactive compounds.
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Hi I would like to know if the extinction coefficient value of this molecule available. Thanks
1 answer-
Helpful?
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Hi. Is this product stable at 4 degrees for a few days? Thanks
1 answer-
The storage temperature is deliberately conservative for long term storage and is set at -20°C for this item. Unfortunately, storage at alternate conditions such as 4°C have not been assessed for this product.
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