Skip to Content
Merck
All Photos(1)

Documents

N8130

Sigma-Aldrich

4-Nitrophenyl acetate

esterase substrate, chromogenic, ≥98% (TLC), powder or crystals

Synonym(s):

Acetic acid 4-nitrophenyl ester

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
CH3CO2C6H4NO2
CAS Number:
830-03-5
Molecular Weight:
181.15
Beilstein:
515874
EC Number:
212-593-5
MDL number:
MFCD00007326
UNSPSC Code:
12352204
PubChem Substance ID:
24897853
NACRES:
NA.32

product name

4-Nitrophenyl acetate, esterase substrate

Assay

≥98% (TLC)

form

powder or crystals

mp

75-77 °C (lit.)

storage temp.

−20°C

SMILES string

CC(=O)Oc1ccc(cc1)[N+]([O-])=O

InChI

1S/C8H7NO4/c1-6(10)13-8-4-2-7(3-5-8)9(11)12/h2-5H,1H3

InChI key

QAUUDNIGJSLPSX-UHFFFAOYSA-N

Gene Information

human ... PON1(5444)

Looking for similar products? Visit Product Comparison Guide

Application

4-Nitrophenyl acetate has been used:
  • to evaluate esterase activity in human embryonic kidney cell line
  • in carbonic anhydrase inhibition assay
  • to study its conversion to p-nitrophenol (p-NP) by the esterase activity of bovine serum albumin
  • as a substrate to determine carboxylesterase (CES) activity in mouse liver cells
  • to study the advantages of bioconjugation of cross-linked enzyme aggregates (CLEAs) and magnetic iron oxide nanoparticles (MIONPs) in magnetic CLEAs matrix

Substrates

Chromogenic esterase substrate.

Signal Word

Danger

Hazard Statements

H272,H317,H318

Hazard Classifications

Eye Dam. 1 - Ox. Sol. 3 - Skin Sens. 1

Storage Class Code

5.1B - Oxidizing hazardous materials

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Michelle R Baker et al.
Biochemistry research international, 2011, 739712-739712 (2011-09-16)
Persistent alteration of protein conformation due to interaction with isoflurane may be a novel molecular aspect of preconditioning. We preincubated human serum albumin with isoflurane, dialyzed to release agent, and assessed protein conformation. Susceptibility to chemical modification by methylglyoxal and
Emmanuel Vázquez-Mayorga et al.
International journal of molecular sciences, 17(8) (2016-08-25)
Mutations the in human DJ-1 (hDJ-1) gene are associated with early-onset autosomal recessive forms of Parkinson's disease (PD). hDJ-1/parkinsonism associated deglycase (PARK7) is a cytoprotective multi-functional protein that contains a conserved cysteine-protease domain. Given that cysteine-proteases can act on both
Immunomodulatory, antiglycation and anti-ulcerative properties of Ruellia squarrosa Fenzl Acanthaceae
Afzal K, et al.
Tropical Journal of Pharmaceutical Research, 16(8), 1751-1755 (2017)
Impact of diet on irinotecan toxicity in mice
Mallick P, et al.
Chemico-Biological Interactions, 291, 87-94 (2018)
Oksana Fursova et al.
Annals of botany, 110(1), 47-56 (2012-05-17)
Agrobacterium-mediated transformation is widely used to produce insertions into plant genomes. There are a number of well-developed Agrobacterium-mediated transformation methods for dicotyledonous plants, but there are few for monocotyledonous plants. Three hydrolase genes were transiently expressed in Brachypodium distachyon plants
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service