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N0258
N-Nitrosodiethylamine
ISOPAC®
Synonym(s):
Diethylnitrosamine
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1 G
€97.70
About This Item
Linear Formula:
(C2H5)2NNO
CAS Number:
Molecular Weight:
102.14
Beilstein:
1744991
EC Number:
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.25
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Quality Level
form
liquid
bp
177 °C (lit.)
density
0.95 g/mL (lit.)
SMILES string
CCN(CC)N=O
InChI
1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3
InChI key
WBNQDOYYEUMPFS-UHFFFAOYSA-N
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Application
Biochem/physiol Actions
N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. It is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. NDEA is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. It results in various tumors in all animal species.[4] The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
Packaging
Packaged in a 100 mL serum bottle with silicon/PTFE septum and aluminum tear seal.
Caution
Injecting any compatible solvent permits preparation of any desired strength solution without exposure.
Reconstitution
Dissolving the contents in 100 mL of solvent yields a 1% solution.
Legal Information
Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany
ISOPAC of
Product No.
Description
Pricing
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Articles
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What is the Department of Transportation shipping information for this product?
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Is Product N0258, N-nitrosoethylamine, a solid or a liquid? Why is the package size expressed in grams?
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This product is neat liquid. The package size is in grams but can be converted to volume by using the density of 0.95 g/mL.
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How does the storage temperature relate to shipping conditions?
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The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.
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What is the solubility of Product N0258, N-Nitrosodiethylamine?
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According to the chemicals encyclopedia published by the Royal Society of Chemistry, 12th edition, this compound is soluble in water, ether and alcohol.
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How can I store solutions of Product N0258, N-Nitrosodiethylamine?
1 answer-
The product should be stable in neutral solution, but it is unstable with strong acid and heat. N-nitroso amine compounds are relatively stable when dissolved in aqueous solutions at physiological pH. But they are generally light sensitive, so stock solutions should be kept cool and protected from light.
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