Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

721034

Sigma-Aldrich

5-Chloro-3-pyridineboronic acid

≥95%

Synonym(s):

(3-Chloro-5-pyridyl)boronic acid, (3-Chloropyridin-5-yl)boronic acid, (5-Chloropyridin-3-yl)boronic acid, 3-Chloropyridine-5-boronic acid, 5-Chloropyridine-3-boronic acid

Sign Into View Organizational & Contract Pricing

Select a Size

1 G
€87.00

€87.00

Please contact Customer Service for Availability
Request a Bulk Order
All Photos(2)

Select a Size

Change View
1 G
€87.00

About This Item

Empirical Formula (Hill Notation):
C5H5BClNO2
CAS Number:
872041-85-5
Molecular Weight:
157.36
MDL number:
MFCD06798243
UNSPSC Code:
12352103
PubChem Substance ID:
329763814
NACRES:
NA.22

€87.00

Please contact Customer Service for Availability
Request a Bulk Order

Quality Level

100

Assay

≥95%

form

solid

mp

255-260 °C

functional group

chloro

storage temp.

2-8°C

SMILES string

OB(O)c1cncc(Cl)c1

InChI

1S/C5H5BClNO2/c7-5-1-4(6(9)10)2-8-3-5/h1-3,9-10H

InChI key

NJXYBTMCTZAUEE-UHFFFAOYSA-N

Related Categories

Application

5-Chloro-3-pyridineboronic acid can be used as an intermediate:
  • In the preparation of positron emission tomography (PET) radioligand [11C]MK-1064, which is applicable in the orexin-2 receptor imaging.[1]
  • In the synthesis of orexin 2 receptor antagonist (2-SORA) MK-1064.[2]
  • In the preparation of pyridyl-cycloalkyl derived microsomal prostaglandin E synthase-1 inhibitors.[3]
  • In the synthesis of ATAD2 bromodomain inhibitors.[4]

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
WXBD1482V
WXBC6111V
MKBN4272V
MKBD4141V
MKBD4141

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Discovery and optimization of pyridyl-cycloalkyl-carboxylic acids as inhibitors of microsomal prostaglandin E synthase-1 for the treatment of endometriosis
Koppitz M, et al.
Bioorganic & Medicinal Chemistry Letters, 29(18), 2700-2705 (2019)
Discovery of 5″-Chloro-N-[(5,6-dimethoxypyridin-2-yl) methyl]-2, 2′: 5′, 3″-terpyridine-3′-carboxamide (MK-1064): A Selective Orexin 2 Receptor Antagonist (2-SORA) for the Treatment of Insomnia
Roecker AJ, et al.
ChemMedChem, 9(2), 311-322 (2014)
Synthesis of [11C] MK-1064 as a new PET radioligand for imaging of orexin-2 receptor
Gao M, et al.
Bioorganic & Medicinal Chemistry Letters, 26(15), 3694-3699 (2016)
Fragment-based discovery of low-micromolar ATAD2 bromodomain inhibitors
Demont EH, et al.
Journal of Medicinal Chemistry, 58(14), 5649-5673 (2015)

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service