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33993

Supelco

Doramectin

VETRANAL®, analytical standard

Synonym(s):

25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin

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About This Item

Empirical Formula (Hill Notation):
C50H74O14
CAS Number:
Molecular Weight:
899.11
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

storage temp.

−20°C

SMILES string

[H][C@@]12OC/C3=C\C=C\[C@H](C)[C@H](O[C@@H]4C[C@H](OC)[C@@H](O[C@@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)\C(C)=C\CC6C[C@@H](C[C@]7(O6)O[C@@H]([C@@H](C)C=C7)C8CCCCC8)OC(=O)[C@H](C=C(C)[C@H]1O)[C@@]23O

InChI

1S/C50H74O14/c1-27-13-12-16-34-26-57-47-42(51)30(4)21-37(50(34,47)54)48(53)60-36-22-35(63-49(25-36)20-19-29(3)45(64-49)33-14-10-9-11-15-33)18-17-28(2)44(27)61-41-24-39(56-8)46(32(6)59-41)62-40-23-38(55-7)43(52)31(5)58-40/h12-13,16-17,19-21,27,29,31-33,35-47,51-52,54H,9-11,14-15,18,22-26H2,1-8H3/b13-12+,28-17+,34-16+/t27-,29-,31-,32-,35?,36-,37-,38-,39-,40+,41+,42+,43-,44-,45-,46-,47+,49+,50+/m0/s1

InChI key

QLFZZSKTJWDQOS-TTXKVKCHSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Lact. - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Dürdane Kaya et al.
Veterinaria italiana, 46(1), 51-56 (2010-04-15)
The authors used 14 New Zealand rabbits (5 naturally infested rabbits and 9 in-contact rabbits) for Sarcoptes scabiei treatment in this study. Signs, such as itchy ears, eyes, tail and abdominal skin, alopecia and pyoderma, were considered to be the
Jian-Bo Wang et al.
Bioorganic & medicinal chemistry letters, 21(11), 3320-3323 (2011-04-26)
In an attempt to construct a strain that produces doramectin, the loading module of Ave polyketide synthase (PKS) from Streptomyces avermitilis M1 was replaced with a cyclohexanecarboxylic (CHC) unique loading module from phoslactomycin PKS. Additionally, the CHC-CoA biosynthetic gene cassette
Two new doramectin analogs from Streptomyces avermitilis NEAU1069: fermentation, isolation and structure elucidation.
Xiang-Jing Wang et al.
The Journal of antibiotics, 64(8), 591-594 (2011-06-16)
Priscila M S Maia et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 100, 127-130 (2012-03-20)
The doramectin (DOR), which belongs to the avermectins group (AVM), has a high antiparasitic activity and so it has been widely used in food-producing animals. The DOR shows low fluorescence quantum efficiency and as a consequence, chemical derivatization reactions are
Ronald B Davey et al.
Experimental & applied acarology, 56(4), 365-374 (2012-02-22)
Analysis of doramectin concentration in blood serum of pastured cattle injected repeatedly (12 treatments) at two different dosage rates and 28-day intervals throughout the year was used to predict the probability that cattle fever ticks could successfully feed to repletion

Protocols

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

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