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Merck

V900576

Sigma-Aldrich

1,8-二羟基蒽醌

Vetec, reagent grade, 96%

别名:

丹蒽醌, 二羟蒽醌

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About This Item

经验公式(希尔记法):
C14H8O4
CAS号:
分子量:
240.21
Beilstein:
2054727
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
价格与库存信息目前不能提供

等級

reagent grade

產品線

Vetec

化驗

96%

mp

191-193 °C (lit.)

SMILES 字串

Oc1cccc2C(=O)c3cccc(O)c3C(=O)c12

InChI

1S/C14H8O4/c15-9-5-1-3-7-11(9)14(18)12-8(13(7)17)4-2-6-10(12)16/h1-6,15-16H

InChI 密鑰

QBPFLULOKWLNNW-UHFFFAOYSA-N

基因資訊

human ... RXRA(6256)

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法律資訊

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險分類

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

No data available

閃點(°C)

No data available


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jo-Hua Chiang et al.
Chemical research in toxicology, 24(1), 20-29 (2010-12-04)
Anthraquinones have been shown to induce apoptosis in different types of tumor cells, but the mechanisms of danthron-induced cytotoxicity and apoptosis in human gastric cancer cells have not been adequately explored. This study investigated the roles of caspase cascades, ROS
Haitao Zhang et al.
The Journal of biological chemistry, 286(3), 1868-1875 (2010-11-19)
Retinoic X receptor (RXR) is a promising target for drug discovery against cancer and metabolic syndromes. Here, we identified a specific RXRα antagonist, danthron, from the traditional Chinese medicine rhubarb. Danthron repressed all tested RXRα-involved response element transcription, including the
Yong-Soo Kwon et al.
Biological & pharmaceutical bulletin, 27(5), 723-726 (2004-05-11)
Oxidative stress caused by an elevation in reactive oxygen species (ROS) plays an important role in Alzheimer's disease and other neurodegenerative diseases. In this study, we examined the neuroprotective effect of danthron (1,8-dihydroxyanthraquinone) against neurotoxicities induced by beta-amyloid (25-35), excitotoxins
Hui Zhou et al.
Biophysical chemistry, 114(1), 21-26 (2005-03-29)
Danthron is an important natural occurring component in laxative drugs. In this paper, electrochemical investigation of danthron and its interaction with DNA is reported. Via the electrochemical approach assisted by ultraviolet-visible (UV-Vis) spectroscopy, we have proved that danthron intercalates into
Chunyu Qiao et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 70(1), 136-143 (2007-09-11)
The interactions of fish sperm deoxyribonucleic acid (DNA) with anthraquinones, such as chrysophanol, physcion and 1,8-dihydroxy anthraquinone, were investigated by using ethidium bromide (EB) as fluorescence probe. The binding constants of anthraquinones and DNA were obtained by the fluorescence quenching

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