1719500

Withanolide A

United States Pharmacopeia (USP) Reference Standard

• 别名: (5α,6α,7α,22R)-6,7-Epoxy-5,20,22-trihydroxy-1-oxo-ergosta-2,24-dien-26-oic acid δ-lactone, Withaniol
• 经验公式（希尔记法）: C₂₈H₃₈O₆
• CAS号: 32911-62-9
• 分子量: 470.60
• MDL编号: MFCD07779143
• UNSPSC代码: 41116107
• PubChem化学物质编号: 329751511
• NACRES: NA.24

属性

• 等级: pharmaceutical primary standard
• API类: withania somnifera
• 制造商/商品名称: USP
• 应用: pharmaceutical (small molecule)
• 包装形式: neat
• 储存温度: 2-8°C
• SMILES字符串: CC1=C(C)C(=O)O[C@H](C1)[C@](C)(O)[C@H]2CC[C@H]3[C@H]4[C@H](CC[C@]23C)[C@@]5(C)C(=O)C=CC[C@]5(O)[C@H]6O[C@@H]46
• InChI: 1S/C28H38O6/c1-14-13-20(33-24(30)15(14)2)27(5,31)18-9-8-16-21-17(10-12-25(16,18)3)26(4)19(29)7-6-11-28(26,32)23-22(21)34-23/h6-7,16-18,20-23,31-32H,8-13H2,1-5H3/t16-,17-,18-,20+,21-,22-,23-,25-,26-,27+,28-/m0/s1
• InChI key: DXWHOKCXBGLTMQ-SFQAJKIESA-N

说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Withanolide A USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Ashwagandha Root
• Ashwagandha Root Dry Extract
• Ashwagandha Root Powder

生化/生理作用

C₂₈-steroidal lactone that can induce nerve development and improve nervous system function. Potential therapeutic for neurologic disorders like Alzheimer′s and Parkinson′s disease. In primary rat cortical neurons, withanolide A significantly up-regulated IDE levels, a prominent enzyme involved in degrading amyloid β protein, which may help to clear excess amyloid β protein from an Alzheimer′s-inflicted brain.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable