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Merck

1708784

USP

Valsartan Related Compound B

United States Pharmacopeia (USP) Reference Standard

别名:

N-(1-Oxobutyl)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-L-valine, (S)-N-Butyryl-N-{[2′-(1-H-tetrazole-5-yl)-biphenyl-4-yl]methyl}valine

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About This Item

经验公式(希尔记法):
C23H27N5O3
分子量:
421.49
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

valsartan

製造商/商標名

USP

應用

pharmaceutical (small molecule)

格式

neat

SMILES 字串

CCCC(=O)N(Cc1ccc(cc1)-c2ccccc2-c3nnn[nH]3)[C@@H](C(C)C)C(O)=O

InChI

1S/C23H27N5O3/c1-4-7-20(29)28(21(15(2)3)23(30)31)14-16-10-12-17(13-11-16)18-8-5-6-9-19(18)22-24-26-27-25-22/h5-6,8-13,15,21H,4,7,14H2,1-3H3,(H,30,31)(H,24,25,26,27)/t21-/m0/s1

InChI 密鑰

OKAQHVJSXLGXET-NRFANRHFSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

This USP reference standard is intended for use in specified quality tests and assays as specified in the USP compendia.
It is also used in the preparation of standard and system suitability solutions for the determination of organic impurities and performance tests of tablets and capsules, in accordance with the USP monographs, by liquid chromatography (LC) combined with UV detection, of the following:
  • Valsartan
  • Amlodipine and valsartan tablets
  • Valsartan and hydrochlorothiazide tablets
  • Amlodipine, valsartan, and hydrochlorothiazide tablets

In addition, it is used in the assay test of valsartan tablets by LC-UV following the USP monograph “Valsartan Tablets”.

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險聲明

危險分類

Repr. 2 - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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访问文档库

Valsartan Tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 47(5), 4579-4579 (2017)
Valsartan and Hydrochlorothiazide Tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(4), 4580-4580 (2015)
Valsartan
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 33(3), 4577-4577 (2020)
Tablet formulation and development of a validated stability indicating hplc method for quantification of valsartan and hydrochlorthiazide combination.
Kharoaf, M. A. H. E. R., et al.
International Journal of Pharmacy and Pharmaceutical Sciences, 4.3, 284-290 (2012)
Amlodipine and Valsartan Tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(2), 275-275 (2017)

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