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Merck
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主要文件

1012595

USP

人血白蛋白

United States Pharmacopeia (USP) Reference Standard

别名:

白蛋白 人, 重组人血白蛋白, rHSA

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6 MG
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About This Item

经验公式(希尔记法):
C2936H4624N786O889S41
CAS号:
分子量:
66471.53
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24

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等级

pharmaceutical primary standard

分子量

monomer ~67 kDa
66,438 Da

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

−20°C

SMILES字符串

FC(F)(F)C(F)(F)C(F)(F)F

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

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一般描述

重组人白蛋白(rAlbumin Human或rHA)有三个结构域,共585个氨基酸,含有1个色氨酸(Trp214)、1个游离巯基(Cys34)和17个二硫键桥。[1] 重组人白蛋白(USP标准品)按现行药典规定交付。所有为支持本产品而提供的信息,包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持,请访问现行药典网站。

应用

人重组白蛋白USP参考标准品适用于指定的USP法定测试和检测。

它也用于制备标准溶液,用于通过液相色谱和紫外检测器根据美国药典(USP)各论分析人重组白蛋白 [1]
该重组变异建议用于:吸收、分散、代谢和排泄(ADME)药理学研究;细胞培养;药物递送研究;细胞冻存。

生化/生理作用

白蛋白是可见于动物体液和组织及部分植物种子的一类可溶性单体蛋白。 血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白。 血清白蛋白在调节血液的胶体渗透压方面也至关重要。

其他说明

更多信息参见人血清白蛋白
该产品是美国药典生物制品计划的一部分。
可能适用相应的销售限制。

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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rAlbumin human
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 34(1), 5604-5604 (2018)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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