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Merck

PHL89587

蟾毒灵

phyproof® Reference Substance

别名:

3β,14-二羟基-5β,20 (22)-丁二烯醇内酯, 5β,20 (22)-丁二烯醇内酯-3β,14-二醇

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About This Item

经验公式(希尔记法):
C24H34O4
CAS号:
分子量:
386.52
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

primary reference standard

產品線

phyproof® Reference Substance

化驗

≥95.0% (HPLC)

製造商/商標名

PhytoLab

應用

food and beverages

格式

neat

儲存溫度

2-8°C

SMILES 字串

O[C@]([C@@](CC[C@@]1([H])[C@@]2(CC[C@H](O)C1)C)([H])[C@]2([H])CC3)(CC[C@@H]4C(C=C5)=COC5=O)[C@]34C

InChI

1S/C24H34O4/c1-22-10-7-17(25)13-16(22)4-5-20-19(22)8-11-23(2)18(9-12-24(20,23)27)15-3-6-21(26)28-14-15/h3,6,14,16-20,25,27H,4-5,7-13H2,1-2H3/t16-,17+,18-,19+,20-,22+,23-,24+/m1/s1

InChI 密鑰

QEEBRPGZBVVINN-BMPKRDENSA-N

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一般說明

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

法律資訊

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

防範說明

危險分類

Acute Tox. 2 Oral

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

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访问文档库

Hai Rui LingHu et al.
OncoTargets and therapy, 13, 4767-4778 (2020-06-26)
Bufalin is a component of Chinese traditional medicine, Chansu, which is reported to induce cell death among various kinds of tumors. Apoptosis evasion is a common problem of cancer treatment. The proliferation of U-87 and U-373 treated by bufalin combined
Ze-Yi Zheng et al.
Cancer cell, 37(3), 387-402 (2020-03-07)
We report that neurofibromin, a tumor suppressor and Ras-GAP (GTPase-activating protein), is also an estrogen receptor-α (ER) transcriptional co-repressor through leucine/isoleucine-rich motifs that are functionally independent of GAP activity. GAP activity, in turn, does not affect ER binding. Consequently, neurofibromin

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