推荐产品
产品名称
SUPELCOSIL ™ LC-ABZ HPLC 色谱柱, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
材料
stainless steel column
品質等級
agency
suitable for USP L60
產品線
SUPELCOSIL™
特點
endcapped
製造商/商標名
SUPELCOSIL™
包裝
1 ea of
標籤範圍
12.0% carbon loading
參數
≤70 °C temp. limit
400 bar pressure (5801 psi)
技術
HPLC: suitable
長度 × 內徑
15 cm × 4.6 mm
表面積
170 m2/g
表面覆盖率
surface coverage 3.4 μmol/m2
基質
silica gel, spherical particle platform
fully porous particle
基質活性組
amide, alkyl phase
粒徑
5 μm
孔徑
120 Å
pH值範圍
2-7.5
應用
food and beverages
分離技術
reversed phase
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一般說明
SUPELCOSIL LC-ABZ 相具有独特的去活技术,该可为碱性化合物以及酸性、中性和非极性化合物提供出色的反相性能。不需要采取使用同类胺在高离子强度下运行,以及调节流动相的极端 pH 值来抑制硅烷醇活性,就可以在 LC-ABZ 相上获得良好的峰形。
應用
- 奈韦拉平原料药中相关有机杂质的高效液相色谱检测方法的验证。:本文验证了使用SUPELCOSIL™ LC-ABZ HPLC色谱柱评估HIV药物纯度和杂质的方法,展示了该色谱柱的高特异性和重现性(Li et al., 2000)。
- S-腺苷-L-蛋氨酸及其相关代谢物在Hypersil ODS和Supelcosil LC-ABZ固定相上的反相HPLC保留行为的比较研究。:这项比较研究深入探讨了生物活性化合物在SUPELCOSIL™ LC-ABZ上的保留行为,肯定了其在复杂生化分离中的通用性和强大性能(Valkó et al., 1993)。
特點和優勢
• 用于酸性、碱性、两性离子
• 相对于标准反相具有更大的极性保留性
• 独特的选择性
• 硅烷醇去活
• 对于非极性分析物,峰形、柱效和保留性相当于 C8 相
• 相对于标准反相具有更大的极性保留性
• 独特的选择性
• 硅烷醇去活
• 对于非极性分析物,峰形、柱效和保留性相当于 C8 相
法律資訊
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
其他客户在看
J G Ufkes et al.
Pharmacy world & science : PWS, 20(2), 83-87 (1998-05-19)
To study the pharmacokinetics of dextromoramide in long-term opiate addicts on methadone maintenance therapy (MMT) a reverse-phase HPLC technique was developed to monitor dextromoramide and methadone concentrations in plasma simultaneously. After liquid-liquid extraction from plasma, dextromoramide and methadone were determined
Neil C Dias et al.
The Analyst, 128(5), 427-433 (2003-06-07)
The solvation parameter model is used to identify suitable chromatographic models for estimating the octanol-water partition coefficient for neutral compounds of varied structure by reversed-phase liquid chromatography. The stationary phase Supelcosil LC-ABZ with methanol-water mobile phases affords a series of
Murali Pendela et al.
Journal of separation science, 32(20), 3418-3424 (2009-09-19)
Streptomycin (SM) is composed of streptidine, streptose and N-methyl glucosamine sugar moieties. For the determination of SM and its related substances, an ion-pair LC-UV detection method using a Supelcosil LC-ABZ column was developed previously. While analyzing commercial samples, several unknown
D Korakas et al.
Journal of pharmaceutical and biomedical analysis, 12(9), 1141-1145 (1994-09-01)
A series of biologically active peptides and their conjugates with lipidic amino acids were investigated by systematic change of the mobile phase composition using traditional octadecylsilica stationary phase and the newly developed Supelcosil LC-ABZ column. The mobile phases contained various
Ana B Baranda et al.
Journal of chromatography. A, 1031(1-2), 275-280 (2004-04-03)
A high-performance liquid chromatographic method with electrochemical detection was developed for the simultaneous determination of five 1,4-dihydropyridines: amlodipine, nitrendipine, felodipine, lacidipine and lercanidipine. These drugs are widely used in the treatment of hypertension, angina pectoris and the therapy of cerebrovascular
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