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Merck

47782

Supelco

D-α-生育酚琥珀酸酯

analytical standard

别名:

维生素 E 琥珀酸酯

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About This Item

经验公式(希尔记法):
C33H54O5
CAS号:
分子量:
530.78
Beilstein:
4038233
EC號碼:
MDL號碼:
分類程式碼代碼:
12164500
PubChem物質ID:

等級

analytical standard

CofA

current certificate can be downloaded

特點

standard type fat soluble vitamin

包裝

ampule of 100 mg

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

格式

neat

儲存溫度

2-8°C

SMILES 字串

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(=O)CCC(O)=O)c(C)c(C)c2O1

InChI

1S/C33H54O5/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-20-33(8)21-19-28-27(7)31(25(5)26(6)32(28)38-33)37-30(36)18-17-29(34)35/h22-24H,9-21H2,1-8H3,(H,34,35)/t23-,24-,33-/m1/s1

InChI 密鑰

IELOKBJPULMYRW-NJQVLOCASA-N

一般說明

D-α-生育酚琥珀酸酯是一种强效的生育酚抗氧化剂,具有抗肿瘤活性,并可抑制结肠癌肝转移。

應用

有关合适的仪器技术的更多信息,请参阅产品的分析证书。如需进一步支持,请联系技术服务。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

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Vitamin E succinate inhibits colon cancer liver metastases
Barnett TK, et al.
The Journal of Surgical Research, 106(2), 292-298 (2002)
Vitamin E succinate promotes breast cancer tumor dormancy
Malafa PM, et al.
The Journal of Surgical Research, 93(1), 163-170 (2000)
Dasheng Wang et al.
Journal of medicinal chemistry, 52(18), 5642-5648 (2009-08-28)
This study is aimed at the pharmacological exploitation of alpha-tocopheryl succinate (1) to develop potent antiadhesion agents. Considering the structural cooperativity between the phytyl chain and the carboxylic terminus in determining the antiadhesion activity, our structural optimization led to compound
Pengfei Xu et al.
Biomaterials, 35(26), 7574-7587 (2014-06-06)
Metastasis is one of the major obstacles for the successful therapy of breast cancer. Although increased candidate drugs targeting cancer metastasis are tested, their clinical translation is limited by either serve toxicity or low efficacy. In present work, a nano-drug
Yanyun Xu et al.
International journal of pharmaceutics, 495(2), 792-797 (2015-09-28)
Our recent publication showed that VES-dFdC nanocapsules in pure water could be obtained via the self-assembling of VES-dFdC prodrug synthesized by coupling gemcitabine (dFdC) with vitamin E succinate (VES). To prepare the intravenous injection nanoformulation, we present here a novel

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