WH0008518M3
Monoclonal Anti-IKBKAP antibody produced in mouse
clone 6G9, purified immunoglobulin, buffered aqueous solution
别名:
DKFZp781H1425, DYS, ELP1, FD, IKAP, IKI3, TOT1, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
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About This Item
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生物源
mouse
共軛
unconjugated
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
6G9, monoclonal
形狀
buffered aqueous solution
物種活性
human
技術
ELISA: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: 1-5 μg/mL
同型
IgG1κ
GenBank登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... IKBKAP(8518)
免疫原
IKBKAP (NP_003631, 1242 a.a. ~ 1331 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VLFLFEFDEQGRELQKAFEDTLQLMERSLPEIWTLTYQQNSATPVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKINRRTQWKLSLL
Sequence
VLFLFEFDEQGRELQKAFEDTLQLMERSLPEIWTLTYQQNSATPVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKINRRTQWKLSLL
生化/生理作用
The protein encoded by this gene is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. (provided by RefSeq)
外觀
Solution in phosphate buffered saline, pH 7.4
法律資訊
GenBank is a registered trademark of United States Department of Health and Human Services
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Dimerization of elongator protein 1 is essential for Elongator complex assembly.
Proceedings of the National Academy of Sciences of the USA, 112(34), 10697-10702 (2015)
Phosphatidylserine increases IKBKAP levels in a humanized knock-in IKBKAP mouse model.
Human Molecular Genetics, 22(14), 2785-2794 (2013)
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