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Merck

IKBKAP

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein

Synonyms:
DYS, ELP1, FD, IKAP, IKI3, TOT1
Species:
Human IKBKAP (8518), Mouse Ikbkap (230233), Rat Ikbkap (140934), domestic cat IKBKAP (101089153), domestic guinea pig Ikbkap (100728587), cow IKBKAP (505465), Domestic Rabbit IKBKAP (100009360), chicken IKBKAP (427375), naked mole-rat Ikbkap (101723104), sheep IKBKAP (101115680) ...More
UniProtKB ID:
O95163, Q5JSV2, Q9H327, Q9UG87
Gene ID:
  • Human(8518) Summary: The protein encoded by this gene is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. [provided by RefSeq, Jul 2008]
  • Mouse(230233) inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein
  • Rat(140934) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
  • domestic cat(101089153) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
  • domestic guinea pig(100728587) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
  • cow(505465) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
  • Domestic Rabbit(100009360) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
  • chicken(427375) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
  • naked mole-rat(101723104) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
  • sheep(101115680) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
  • dog(612455) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
  • Zebrafish(561039) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
  • Horse(100053999) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein

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Antibodies

Product Number
Description
Species Reactivity
Application
WH0008518M3
Monoclonal Anti-IKBKAP antibody produced in mouse, clone 6G9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
PRS2337
Anti-IKAP antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry
immunofluorescence
western blot
HPA049677
Anti-IKBKAP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
HPA050686
Anti-IKBKAP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
EMU086241
MISSION® esiRNA, targeting mouse Ikbkap,
Species
mouse
EHU156451
MISSION® esiRNA, targeting human IKBKAP,
Species
human