V0377

[Arg⁸]-Vasopressin solution

Grade VI (synthetic), ~100 IU/mL in 0.9% NaCl

• 别名: β-Hypophamine, AVP, Antidiuretic hormone, Arginine vasopressin
• 经验公式（希尔记法）: C₄₆H₆₅N₁₅O₁₂S₂
• CAS号: 113-79-1
• 分子量: 1084.23
• MDL號碼: MFCD00076738
• 分類程式碼代碼: 51111800
• PubChem物質ID: 24900692
• NACRES: NA.32

属性

• 生物源: synthetic (organic)
• 品質等級: 200
• 無菌: non-sterile
• 種類: Grade VI (synthetic)
• 形狀: liquid
• 包含: 0.4% 4-chlorobutanol as preservative
• 濃度: ~100 IU/mL in 0.9% NaCl
• pH值: ~3.5
• UniProt登錄號: P01185
• 運輸包裝: ambient
• 儲存溫度: 2-8°C
• SMILES 字串: NC1CSSCC(NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc3ccc(O)cc3)NC1=O)C(=O)N4CCCC4C(=O)NC(CCCNC(N)=N)C(=O)NCC(N)=O
• InChI: 1S/C46H65N15O12S2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)
• InChI 密鑰: KBZOIRJILGZLEJ-UHFFFAOYSA-N
• 基因資訊: human ... AVP(551)

说明

Amino Acid Sequence

Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 [Disulfide Bridge: 1-6]

應用

[Arg⁸]-Vasopressin solution was used as an antigen for preparing preadsorbed antisera for immunocytochemistry. The product was used in L6 cell culture of the C5 subclone for differentiation studies.

生化／生理作用

Endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. Arg⁸-vasopressin is also a neurotransmitter in the central nervous system. It is implicated in a variety of physiological processes including diuresis, vasoregulation, and memory. Regulates water balance by antidiuretic action; contracts arterioles (vasopressor action).

[Arg⁸]-Vasopressin solution also known as Antidiuretic hormone, Arginine vasopressin or beta-Hypophamine is a selective and potent vasopressor agent that stabilizes the cardiocirculatory function in normal human as well as in patients suffering from catecholamine-resistant vasodilatory shock. It stimulates three acid-base transporters and hence increases the capability of the cell to regulate pH.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 235.4 °F - closed cup
• 閃點（°C）: 113 °C - closed cup