This product may be reconstituted in 0.01M phosphate buffer at pH 7.5. Stock solutions, prepared at 10 micro IU per milliliter, may be stored frozen in aliquots. Avoid repeated freeze/thaw cycles. Working solutions should be prepared fresh and not stored.
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生物来源
human pituitary glands
质量水平
无菌性
non-sterile
表单
lyophilized powder
比活
≥6.2 IU/mg (immunoassay, non-sterile)
储存条件
(Keep container tightly closed in a dry and well-ventilated place)
技术
cell culture | mammalian: suitable
杂质
HIV Antibodies
Antibody to HCV
Antibody to HBV or Presence of HBSAG, tested negative
运输
ambient
储存温度
2-8°C
基因信息
human ... TSHB(7252) , TSHR(7253)
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一般描述
生化/生理作用
双链糖蛋白激素。α-链是不具有活性的，生物特异性是因为β-链。激活甲状腺中的腺苷酸环化酶，刺激碘摄取、甲状腺素合成和释放。致甲状腺肿大。
包装
包装规格取决于激素
外形
含有激素和盐（来自约 0.1 mL 的 0.05 M 磷酸盐缓冲液，pH 7.4）。
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Physiology, Thyroid Stimulating Hormone
Pirahanchi Y, et al.
StatPearls [Internet] (2022)
J Carretero et al.
Histology and histopathology, 4(1), 71-76 (1989-01-01)
The TSH-producing adenohypohyseal cells of Wistar rats were studied after treatment with orally administered methymazole by the PAP immunocytochemical method. These cells were compared with those of normal animals. The effects of methymazole were different in the females to those
D Manole et al.
The Journal of clinical endocrinology and metabolism, 86(3), 1072-1077 (2001-03-10)
Thyroid tumors are about 3 times more frequent in females than in males. Epidemiological studies suggest that the use of estrogens may contribute to the pathogenesis of thyroid tumors. In a very recent study a direct growth stimulatory effect of
Thyroid-stimulating hormone
The pituitary, 163-201 (2017)
Jianqing Liang et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 9(9), e2105568-e2105568 (2022-01-23)
Euthyroidism is of profound importance for lifetime health. However, the early diagnosis or therapeutics of thyroid developmental defects has not been established, mainly due to limited understanding of human thyroid development and a lack of recapitulating research model. Herein, the
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