推荐产品
方案
≥95% (HPLC)
表单
powder
分子量
59670 g/mol
技术
toxicology assay: suitable
溶解性
DMF: 20 mg/mL, clear, colorless to yellow
适用性
suitable for molecular biology
储存温度
−20°C
SMILES字符串
CSCC[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc3ccccc3)C(N)=O
InChI
1S/C29H36N6O6S/c1-42-12-11-22(33-27(39)20(30)14-18-16-32-21-10-6-5-9-19(18)21)28(40)35-24(15-25(36)37)29(41)34-23(26(31)38)13-17-7-3-2-4-8-17/h2-10,16,20,22-24,32H,11-15,30H2,1H3,(H2,31,38)(H,33,39)(H,34,41)(H,35,40)(H,36,37)/t20-,22-,23-,24-/m0/s1
InChI key
RGYLYUZOGHTBRF-BIHRQFPBSA-N
基因信息
human ... CCK(885)
rat ... Cckbr(25706)
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Amino Acid Sequence
Trp-Met-Asp-Phe-NH2
一般描述
应用
生化/生理作用
包装
无底玻璃瓶。内含物装在插入的融合锥内。
制备说明
胆囊收缩素片段 30-33 酰胺溶于二甲基甲酰胺中，浓度为 20 mg/ml，得到澄清、无色至黄色的溶液。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
H Fink et al.
Experimental brain research, 123(1-2), 77-83 (1998-12-03)
Cholecystokinin (CCK) is one of the first discovered gastrointestinal hormones and one of the most abundant neuropeptides in the brain. Two types of CCK receptors have been identified: (1) CCK-A receptors are mainly located in the periphery, but are also
Kim Hinkelmann et al.
Journal of psychiatric research, 44(16), 1148-1153 (2010-05-11)
Cholecystokinin-tetrapeptide (CCK-4) is an established model to generate subjective panic anxiety. CCK-4 injection also results in consistent and dose-dependent rise of stress hormones. Effects other than upon subjective panic and stress hormone activity have barely been examined. The purpose of
Cannabinoid receptors and cholecystokinin in feeding inhibition
Francisco A, et al.
Vitamins and Hormones (2013)
Rainer Rupprecht et al.
Science (New York, N.Y.), 325(5939), 490-493 (2009-06-23)
Most antianxiety drugs (anxiolytics) work by modulating neurotransmitters in the brain. Benzodiazepines are fast and effective anxiolytic drugs; however, their long-term use is limited by the development of tolerance and withdrawal symptoms. Ligands of the translocator protein [18 kilodaltons (kD)]
M Bläker et al.
Molecular pharmacology, 58(2), 399-406 (2000-07-25)
Recent efforts have focused on identifying small nonpeptide molecules that can mimic the activity of endogenous peptide hormones. Understanding the molecular basis of ligand-induced receptor activation by these divergent classes of ligands should expedite the process of drug development. Using
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