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Merck

T6442

Sigma-Aldrich

抗-TRPC6 兔抗

affinity isolated antibody, lyophilized powder

别名:

抗-瞬时受体电位阳离子通道,亚族C,成员6 兔抗

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

lyophilized powder

物種活性

mouse, rat

技術

immunohistochemistry: suitable using mouse brain sections
western blot: 1:200-1:400 using rat brain or lung lysates

UniProt登錄號

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... TRPC6(7225)
mouse ... Trpc6(22068)
rat ... Trpc6(89823)

免疫原

对应于小鼠 TRPC6 的氨基酸残基 24-38 的合成肽(RRNESQDYLLMDELG)。该序列在大鼠中是相同的,在人类中是高度同源的(15/16 个残基相同)。

外觀

从含有1%牛血清白蛋白和0.05%叠氮化钠的磷酸盐缓冲盐水(pH 7.4)中冻干。

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Yonghong Bai et al.
eLife, 9 (2020-03-10)
Transient receptor potential canonical (TRPC) proteins form nonselective cation channels that play physiological roles in a wide variety of cells. Despite growing evidence supporting the therapeutic potential of TRPC6 inhibition in treating pathological cardiac and renal conditions, mechanistic understanding of
Chengkang He et al.
JCI insight, 7(5) (2022-01-26)
Currently, the most effective strategy for dealing with Alzheimer's disease (AD) is delaying the onset of dementia. Severe hypoglycemia is strongly associated with dementia; however, the effects of recurrent moderate hypoglycemia (RH) on the progression of cognitive deficits in patients
Yanna Du et al.
Molecular medicine reports, 16(2), 1117-1124 (2017-06-20)
Persistent pulmonary hypertension of the newborn (PPHN) is a life‑threatening disease that is commonly observed in the neonatal intensive care unit. PPHN is pathologically characterized by pulmonary vascular remodeling and, in particular, pulmonary artery smooth muscle cell (PASMC) proliferation. Decreased
Ying Meng et al.
International journal of molecular medicine, 37(1), 258-266 (2016-01-01)
Ischemia-reperfusion (I/R) plays an important role in myocardial injury. In the present study, we aimed to examine the protective effects of Danshensu (DSS) against I/R injury and to elucidate the underlying mechanisms. For this purpose, H9c2 cells were cultured in hypoxic solution
M Salomonsson et al.
Acta physiologica (Oxford, England), 200(3), 265-278 (2010-04-30)
In rat afferent arterioles we investigated the role of Na(+) entry in noradrenaline (NA)-induced depolarization and voltage-dependent Ca(2+) entry together with the importance of the transient receptor potential channel (TRPC) subfamily for non-voltage-dependent Ca(2+) entry. R (340/380) Fura-2 fluorescence was

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