T2080

TRKB (455-end), active, GST tagged human

PRECISIO^® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• 别名: GP145-TrkB, NTRK2
• UNSPSC代码: 12352200
• NACRES: NA.32

属性

• 重组: expressed in baculovirus infected Sf9 cells
• 质量水平: 200
• 产品线: PRECISIO^® Kinase
• 方案: ≥70% (SDS-PAGE)
• 表单: buffered aqueous glycerol solution
• 比活: 63-85 nmol/min·mg
• 分子量: ~67 kDa
• UniProt登记号: Q16620
• 运输: dry ice
• 储存温度: −70°C
• 基因信息: human ... NTRK2(4915)

说明

生化/生理作用

TRKB is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. TRKB is the high affinity catalytic receptor for several "neurotrophins", which are small protein growth factors that induce the survival and differentiation of distinct cell populations. TRKB is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signaling through TRKB leads to cell differentiation. Mutations in the TRKB gene have been associated with obesity and mood disorders.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律信息

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable