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生物来源
rat
重组
expressed in E. coli
方案
≥90% (HPLC)
≥90% (SDS-PAGE)
表单
lyophilized
效能
<0.01 ng/mL ED50
分子量
~21.7 kDa
包装
pkg of 10 μg
杂质
endotoxin, tested
NCBI登记号
运输
wet ice
储存温度
−20°C
基因信息
rat ... Il6(24498)
一般描述
Interleukin- 6 (IL-6) is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. It is a pro-inflammatory cytokine. IL-6 originates from mononuclear phagocytes, T and B lymphocytes, vascular endothelial cells and fibroblasts. It has a role in various physiological and pathological processes. IL-6 plays an important role in intracellular signaling pathways.[1][2] Recombinant rat IL-6 is a 21.7kDa protein containing 187 amino acid residues.
外形
Lyophilized without any additives.
重悬
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in 10 mM HCl to a concentration of 0.1-1.0 μg/μL. The solution can then be diluted into other aqueous buffers.
历史批次信息供参考:
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Liu TZ
Medicine (2017)
Elin Banke et al.
Metabolism: clinical and experimental, 63(6), 831-840 (2014-04-02)
The bacteria Staphylococcus aureus is part of the normal bacterial flora and produces a repertoire of enterotoxins which can cause food poisoning and toxic shock and might contribute to the pathogenesis of inflammatory diseases. These enterotoxins directly cross-link the T
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