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生物源
human
重組細胞
expressed in E. coli
化驗
≥95% (SDS-PAGE)
形狀
lyophilized
效力
≥2x10^6 units/mg
分子量
~22.4 kDa
包裝
pkg of 25 μg
儲存條件
avoid repeated freeze/thaw cycles
雜質
endotoxin, tested
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... FGF8(2253)
一般說明
Fibroblast growth factor-8 (FGF-8) is also known as androgen-induced growth factor (AIGF). It is a heparin-binding growth factor. The gene encoding this protein is localized on human chromosome 10.[1] Recombinant human FGF-8 is a 22.4kDa protein containing 193 amino acid residues.
生化/生理作用
外觀
Lyophilized in 10 mM Tris, pH 8.0 plus 75 mM NaCl. The protein may appear as a haze or film, which may not be seen at the bottom of the vial.
重構
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in 5 mM Tris, pH 8.0 to a concentration of 0.1-1 mg/mL. This solution can be diluted into other aqueous buffers.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
历史批次信息供参考:
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Karolina Jendryczko et al.
Frontiers in pharmacology, 12, 748936-748936 (2021-12-07)
Targeted therapies are a promising alternative to conventional chemotherapy, with an increasing number of therapeutics targeting specific molecular aberrancies in cancer cells. One of the emerging targets for directed cancer treatments is fibroblast growth factor receptors (FGFRs), which are known
Screening a phage display library for a novel FGF8b-binding peptide with anti-tumor effect on prostate cancer.
Wang W
Experimental Cell Research, 319(8), 1156-1164 (2013)
A novel locus of ectodermal dysplasia maps to chromosome 10q24.32-q25.1.
Rafiq MA
The Journal of Investigative Dermatology, 124(2), 338-342 (2005)
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