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生物来源
rat
重组
expressed in E. coli
方案
≥97% (HPLC)
≥97% (SDS-PAGE)
表单
lyophilized
效能
<0.2 ng/mL
分子量
~16.3 kDa
包装
pkg of 50 μg
储存条件
avoid repeated freeze/thaw cycles
杂质
endotoxin, tested
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
rat ... Fgf2(54250)
一般描述
Fibroblast growth factor-2 (FGF-2) is a basic heparin binding growth factor and a profibrotic factor.[1] The recombinant mouse FGF-2 is a single, non-glycosylated chain containing 145 amino acids and having a molecular weight of 16.3kDa.
生化/生理作用
Fibroblast growth factor-2 (FGF-2) stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells.[2]
外形
Lyophilized from 1 mg/ml solution after extensive dialysis against 20 mM phosphate buffer, pH 7.4 and 130 mM NaCl.
重悬
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in sterile water to 0.1–1 mg/mL.
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Apocynin Attenuates Cardiac Injury in Type 4 Cardiorenal Syndrome via Suppressing Cardiac Fibroblast Growth Factor-2 With Oxidative Stress Inhibition.
Liu Y
Journal of the American Heart Association, 4(7), e001598-e001598 (2015)
FGF-18, a novel member of the fibroblast growth factor family, stimulates hepatic and intestinal proliferation.
Hu MC
Molecular and Cellular Biology, 18(10), 6063-6074 (1998)
Senthil S Saravanamuthu et al.
Developmental biology, 332(1), 166-176 (2009-06-02)
Previous studies of the developing lens have shown that Notch signaling regulates differentiation of lens fiber cells by maintaining a proliferating precursor pool in the anterior epithelium. However, whether Notch signaling is further required after the onset of fiber cell
Larisa Antonova et al.
Pharmaceuticals (Basel, Switzerland), 14(4) (2021-04-04)
Tissue-engineered vascular grafts are widely tested as a promising substitute for both arterial bypass and replacement surgery. We previously demonstrated that incorporation of VEGF into electrospun tubular scaffolds from poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/poly(ε-caprolactone) enhances formation of an endothelial cell monolayer. However, an overdose
Yayoi Yoshimura et al.
PloS one, 10(6), e0128288-e0128288 (2015-06-04)
Glioblastoma multiforme (GBM) is associated with high mortality due to infiltrative growth and recurrence. Median survival of the patients is less than 15 months, increasing requirements for new therapies. We found that both arsenic trioxide and 10058F4, an inhibitor of
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