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Merck
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主要文件

SRP0386

Sigma-Aldrich

NSD1 human

recombinant, expressed in E. coli, ≥63% (SDS-PAGE)

别名:

KMT3B, STO, nuclear receptor binding SET domain protein 1

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About This Item

UNSPSC代码:
12352202
NACRES:
NA.32
价格与库存信息目前不能提供

生物来源

human

重组

expressed in E. coli

方案

≥63% (SDS-PAGE)

表单

aqueous solution

分子量

54 kDa

包装

pkg of 50 μg

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... NSD1(64324)

一般描述

Human NSD1 (GenBank Accession No. NM_022455), amino-acids 1849-2094 with N-terminal GST tag, MW = 54 kDa, expressed in an E.coli expression system.

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

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Toshiko Yamada-Okabe et al.
Cell biochemistry and function, 26(2), 146-150 (2007-04-18)
Nuclear receptor-binding SET-domain-containing protein 1 (NSD1), a culprit gene for Sotos syndrome, contains a su(var)3-9, enhancer-of-zeste, trithorax (SET) domain that is responsible for histone methyltransferase activity and other domains such as plant homeodomain (PHD) and proline-tryptophan-tryptophan-proline (PWWP) involved in protein-protein
Pascale Saugier-Veber et al.
Human mutation, 28(11), 1098-1107 (2007-06-15)
Sotos syndrome is an overgrowth syndrome characterized by distinctive facial features, learning difficulties, and macrocephaly with frequent pre- and postnatal overgrowth with advanced bone age. Here, we report on our experience in the molecular diagnostic of Sotos syndrome on 116

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