SML3314
PF-00835231
≥98% (HPLC)
别名:
; N-((S)-1-((S)-4-Hydroxy-3-oxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-ylamino)-4-methyl-1-oxopentan-2-yl)-4-methoxy-1H-indole-2-carboxamide, N-[(1S)-1-[[[(1S)-3-Hydroxy-2-oxo-1-[[(3S)-2-oxo-3-pyrrolidinyl]methyl]propyl]amino]carbonyl]-3-methylbutyl]-4-methoxy-1H-indole-2-carboxamide, PF 00835231, PF 835231, PF-835231, PF00835231, PF835231
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About This Item
推荐产品
品質等級
化驗
≥98% (HPLC)
形狀
powder
顏色
white to beige
溶解度
DMSO: 2 mg/mL, clear
儲存溫度
2-8°C
SMILES 字串
COC1=C2C(NC(C(N[C@@H](CC(C)C)C(N[C@H](C(CO)=O)C[C@H]3C(NCC3)=O)=O)=O)=C2)=CC=C1
生化／生理作用
Potent and selective corona virus hCoV, SARS CoV-1 & CoV-2 main protease (Mpro; 3CLpro) substrate site Cys145 covalent inhibitor with low host cytotoxicity.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Robert L Hoffman et al.
Journal of medicinal chemistry, 63(21), 12725-12747 (2020-10-16)
The novel coronavirus disease COVID-19 that emerged in 2019 is caused by the virus SARS CoV-2 and named for its close genetic similarity to SARS CoV-1 that caused severe acute respiratory syndrome (SARS) in 2002. Both SARS coronavirus genomes encode
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