SML1504

Tegaserod maleate

≥98% (HPLC)

• 别名: 2-[(5-Methoxy-1H-indol-3-yl)methylene]-N-pentyl-hydrazinecarboximidamide maleate
• 经验公式（希尔记法）: C₁₆H₂₃N₅O · C₄H₄O₄
• CAS号: 189188-57-6
• 分子量: 417.46
• MDL號碼: MFCD09028009
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825925
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 20 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: N=C(NCCCCC)N/N=C/C1=CNC2=C1C=C(OC)C=C2.OC(/C=C\C(O)=O)=O
• InChI: 1S/C16H23N5O.C4H4O4/c1-3-4-5-8-18-16(17)21-20-11-12-10-19-15-7-6-13(22-2)9-14(12)15;5-3(6)1-2-4(7)8/h6-7,9-11,19H,3-5,8H2,1-2H3,(H3,17,18,21);1-2H,(H,5,6)(H,7,8)/b20-11+;2-1-
• InChI 密鑰: CPDDZSSEAVLMRY-FEQFWAPWSA-N
• 基因資訊: human ... HTR4(3360)

说明

應用

Tegaserod maleate has been used to study its cytotoxic effects on human astrocytes and to study its effects as an anti-glioblastoma agent.

生化／生理作用

It stimulates neurotransmitter release from enteric nerves and regularizes gastrointestinal function. Tegaserod has been used to treat irritable bowel syndrome associated with constipation and chronic constipation.

Tegaserod is a potent full agonist at serotonin 5-HT4 receptors with an EC₅₀ of 7 nM.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable