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Merck

SML1322

Sigma-Aldrich

Ipamorelin acetate

≥98%

别名:

2-Methylalanyl-L-histidyl-3-(2-naphthalenyl)-D-alanyl-D-phenylalanyl-L-lysinamide acetate, Aib-His-D-2-Nal-D-Phe-Lys-NH2 acetate, NNC 26-0161 acetate;

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About This Item

经验公式(希尔记法):
C38H49N9O5 · xC2H4O2
分子量:
711.85 (free base basis)
分類程式碼代碼:
51111800
NACRES:
NA.77

品質等級

化驗

≥98%

形狀

powder

顏色

white to beige

溶解度

H2O: 20 mg/L, clear

運輸包裝

wet ice

儲存溫度

−20°C

生化/生理作用

Ipamorelin is a selective growth hormone secretagogue and agonist of the ghrelin receptor that selectively stimulates the ghrelin receptor and causes growth hormone release. The potency and efficacy of ipamorelin are similar to GHRP-6 but without increase plasma levels of ACTH or cortisol. Ipamorelin appears to enter the central nervous system and to activate GRLN receptors in the spinal cord.
Ipamorelin is known to be useful in reducing the symptoms of postoperative ileus is a gastrointestinal dysfunction arising due to abdominal surgery. Symptoms include abdominal distention, vomiting, nausea, constipation and anorexia.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Kalina Venkova et al.
The Journal of pharmacology and experimental therapeutics, 329(3), 1110-1116 (2009-03-18)
Ghrelin and ghrelin mimetics stimulate appetite and enhance gastric motility. The present study investigates whether ipamorelin, a selective growth hormone secretagogue and agonist of the ghrelin receptor, would accelerate gastrointestinal transit and ameliorate the symptoms in a rodent model of

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