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Merck
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主要文件

SML0983

Sigma-Aldrich

5F-203

≥98% (HPLC)

别名:

4-(5-Fluoro-2-benzothiazolyl)-2-methyl-benzenamine, 5F203, NSC-703786

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About This Item

经验公式(希尔记法):
C14H11FN2S
分子量:
258.31
UNSPSC代码:
12352200
NACRES:
NA.77
价格与库存信息目前不能提供

质量水平

方案

≥98% (HPLC)

表单

powder

颜色

white to beige

溶解性

DMSO: 20 mg/mL, clear

储存温度

2-8°C

SMILES字符串

Fc1cc2nc([s]c2cc1)c3cc(c(cc3)N)C

InChI

1S/C14H11FN2S/c1-8-6-9(2-4-11(8)16)14-17-12-7-10(15)3-5-13(12)18-14/h2-7H,16H2,1H3

InChI key

IFWLHIIUGSEKKE-UHFFFAOYSA-N

生化/生理作用

5F-203 is a cytotoxic molecule that forms DNA adducts that lead to cell death.
5F-203 is a cytotoxic molecule that forms DNA adducts that lead to cell death. 5F-203 induces aryl hydrocarbon receptor signaling, and elevates expression of CYP1A1. Treatment of cells with 5F-203 also leads to elevation of reactive oxygen species and activation of p38, JNK and ERK.

特点和优势

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

象形图

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警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Cell cycle phases (G1, S, G2, M) regulate cell growth, DNA replication, and division in proliferating cells.

Apoptosis regulation involves multiple pathways and molecules for cellular homeostasis.

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