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Merck

SML0640

Sigma-Aldrich

2-Methylserotonin maleate

≥95% (HPLC)

别名:

2-Me-5-HT maleate, 2-Methyl-5-HT maleate, 2-Methyl-5-hydroxytryptamine maleate

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5 MG
$94.70
25 MG
$337.00

About This Item

经验公式(希尔记法):
C11H14N2O · C4H4O4
CAS号:
分子量:
306.31
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

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质量水平

方案

≥95% (HPLC)

表单

powder

储存条件

desiccated

颜色

white to brown

溶解性

H2O: 5 mg/mL, clear

储存温度

2-8°C

SMILES字符串

OC1=CC2=C(NC(C)=C2CCN)C=C1.OC(/C=C\C(O)=O)=O

InChI

1S/C11H14N2O.C4H4O4/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7;5-3(6)1-2-4(7)8/h2-3,6,13-14H,4-5,12H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

KFEAUMZKRNJEDU-BTJKTKAUSA-N

生化/生理作用

2-Methylserotonin is a 5-HT3 serotonin receptor agonist.
2-Methylserotonin is a selective full agonist at the 5-HT3 receptor.
2-Methylserotonin maleate, a serotonin type 3 (5-HT3) agonist is used as a training drug in drug discrimination studies.[1] Use of 2-methylserotonin in evolving rats shows to reflect the ontogeny of the spinal 5-HT3 receptor system.[2]

特点和优势

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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5-HT3 agonist 2-methylserotonin as a training drug in drug discrimination studies
Glennon R A et al.
Pharmacology, Biochemistry, and Behavior, 41(2), 361-364 (1992)
Antinociceptive effects of intrathecally administered 2-methylserotonin in developing rats
Giordano J
Dev. Brain Res., 98(1), 142-144 (1997)

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