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品質等級
化驗
≥98% (HPLC)
形狀
powder
顏色
faintly yellow to dark yellow
溶解度
DMSO: >5 mg/mL (warmed)
儲存溫度
−20°C
SMILES 字串
CN1C(C(=O)Nc2ccccn2)=C(O)c3sc(Cl)cc3S1(=O)=O
InChI
1S/C13H10ClN3O4S2/c1-17-10(13(19)16-9-4-2-3-5-15-9)11(18)12-7(23(17,20)21)6-8(14)22-12/h2-6,18H,1H3,(H,15,16,19)
InChI 密鑰
WLHQHAUOOXYABV-UHFFFAOYSA-N
一般說明
Lornoxicam belongs to the oxicam class. It has anti-inflammatory and antipyretic properties. Lornoxicam prevents the synthesis of prostaglandin (PG) by inhibiting cyclo-oxygenase. It is used to relieve various types of symptoms associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute sciatica and low back pain.
應用
Lornoxicam has been used as a drug in melanin binding study with cassette dosing and rapid equilibrium dialysis inserts.
生化／生理作用
Lornoxicam is an oxicam-class NSAID with strong analgesic properties.
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 2 Oral
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Jianjun Zhang et al.
Pakistan journal of pharmaceutical sciences, 25(2), 371-375 (2012-03-31)
A rapid, isocratic stability indicating high performance liquid chromatographic method was developed and validated for the estimation of lornoxicam in its powder for injection. The analysis was performed on a Shimadzu VP-ODS (4. 6 mm x 15 cm, 5 µm)
M Arslan et al.
Bratislavske lekarske listy, 113(4), 211-213 (2012-04-17)
Lornoxicam and iv paracetamol are commonly preferred to be used for postoperative analgesia. Although Aspirin is a well known non-steroid anti-inflammatory drug that decreases the erythrocyte deformability, there is no study comparing lornoxicam and iv paracetamol regarding their effects on
Susanne Schroeder et al.
Rheumatology international, 32(9), 2661-2667 (2011-07-27)
The local tolerability of lornoxicam (Xefo) after single and repeated intraarticular administration was assessed in the rabbit and compared to established standard therapies (hyaluronic acid--Synvisc and the glucocorticoid triamcinolone--Triam), and the results are discussed in the context of the literature.
Mustafa Arslan et al.
Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 23(4), 160-166 (2012-02-01)
The purpose of the present study was to determine the efficacy of intravenous (iv) paracetamol and iv lornoxicam on postoperative analgesia and the reduction in tramadol consumption. Sixty patients (ASA class 1-2, age: 18-72 years) undergoing thyroidectomy were enrolled in
Hany A Mowafi et al.
World journal of surgery, 36(9), 2039-2044 (2012-05-16)
The aim of this prospective, randomized, double-blind study was to determine the more effective supplemental analgesic, paracetamol or lornoxicam, for postoperative pain relief after lower abdominal surgery. Sixty patients scheduled for lower abdominal surgery under general anesthesia were randomly allocated
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