SML0014

Scutellarin hydrate

≥98% (HPLC)

• 别名: 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-ß-D-glucopyranosiduronic acid hydrate, 7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one hydrate, Breviscapin, Scutellarein-7-O-β-D-glucuronide
• 经验公式（希尔记法）: C₂₁H₁₈O₁₂ · xH₂O
• CAS号: 27740-01-8
• 分子量: 462.36 (anhydrous basis)
• UNSPSC代码: 12352200
• NACRES: NA.77

属性

• 方案: ≥98% (HPLC)
• 表单: powder
• 储存条件: desiccated
• 颜色: yellow
• 溶解性: DMSO: ≥10 mg/mL
• 储存温度: 2-8°C
• SMILES字符串: O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1C(=O)O)O)O)O)Oc2cc3c(c(c2O)O)C(=O)C=C(O3)c4ccc(cc4)O
• InChI: 1S/C21H18O12/c22-8-3-1-7(2-4-8)10-5-9(23)13-11(31-10)6-12(14(24)15(13)25)32-21-18(28)16(26)17(27)19(33-21)20(29)30/h1-6,16-19,21-22,24-28H,(H,29,30)/t16-,17-,18+,19-,21+/m0/s1
• InChI key: DJSISFGPUUYILV-ZFORQUDYSA-N

说明

应用

Scutellarin hydrate may be used in MAPK-mediated cell signaling studies.

生化/生理作用

Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS.

特点和优势

This compound is featured on the MAPKs and Nitric Oxide Synthases pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable