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Merck

SMB00584

Sigma-Aldrich

天麻素

from Gastrodia alata, ≥98%

别名:

(2R,3S,4S,5R,6S)-2-羟甲基-6-(4-羟甲基-苯氧基)-四氢-吡喃-3,4,5-三醇, 4-β-D-吡喃葡萄糖氧苄醇, 4-羟基苯甲醇 4-O-β-D-葡萄糖苷

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About This Item

经验公式(希尔记法):
C13H18O7
CAS号:
分子量:
286.28
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.25

化驗

≥98%

形狀

powder

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

2-8°C

SMILES 字串

O[C@@H]1[C@@H](CO)O[C@@H](OC2=CC=C(CO)C=C2)[C@H](O)[C@H]1O

InChI

1S/C13H18O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/m1/s1

InChI 密鑰

PUQSUZTXKPLAPR-UJPOAAIJSA-N

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一般說明

Gastrodin, a phenolic glucoside, is the main active ingredient of the Traditional Chinese medicinal compound Tianma. Gastrodin can penetrate through the blood-brain barrier and has been suggested to have neuroprotective effects against hypoxia. It is also known to reduce the immunoreactivity of γ-aminobutyric acid shunt enzymes in hippocampal tissues.[1]

生化/生理作用

Gastrodin is a key bioactive component. The study shows that its clinical application is widely distributed in the treatment of neurasthenia, dizziness, epilepsy, migraine, headache and dementia. Its pharmacological impacts has also been reported in cardiovascular diseases and neointima formation.[2]

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ji-Nan Dai et al.
PloS one, 6(7), e21891-e21891 (2011-07-19)
Microglial activation plays an important role in neurodegenerative diseases by producing several proinflammatory enzymes and proinflammatory cytokines. The phenolic glucoside gastrodin, a main constituent of a Chinese herbal medicine, has been known to display anti-inflammatory properties. The current study investigates
Lihua Zhu et al.
International journal of molecular medicine, 30(5), 1034-1040 (2012-08-28)
Vascular smooth muscle cell (VSMC) proliferation plays a critical role in the development of vascular diseases. In the present study, we tested the efficacy and the mechanisms of action of gastrodin, a bioactive component of the Chinese herb Gastrodia elata

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