生物源
rabbit
品質等級
材料
colorless
無性繁殖
5C1P5, monoclonal
形狀
liquid
分子量
115 kDa
物種活性
human, rat, rat
濃度
1
技術
immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000
顏色
colorless
一般說明
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
免疫原
A synthetic peptide corresponding to a sequence within amino acids 717-816 of human ERK5 (Q13164).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
應用
WB, IHC
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
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