SAB4300440

Anti-NFKBIA (Ab-42) antibody produced in rabbit

affinity isolated antibody

• 别名: Anti-IKBA antibody produced in rabbit, Anti-MAD-3 antibody produced in rabbit, Anti-NFKBI antibody produced in rabbit, Anti-nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha antibody produced in rabbit
• MDL编号: MFCD01633603
• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: rabbit
• 偶联物: unconjugated
• 抗体形式: affinity isolated antibody
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 分子量: ~39 kDa
• 种属反应性: human, mouse
• 浓度: 1 mg/mL
• 技术: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; western blot: 1:500-1:1000
• 同位素/亚型: IgG
• 免疫原序列: (E-E-Y-E-Q)
• NCBI登记号: NP_065390.1
• UniProt登记号: P25963
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... NFKBIA(4792)

说明

免疫原

Peptide sequence around aa. 40-44 (E-E-Y-E-Q), according to the protein NFKBIA.

特点和优势

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目标描述

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable