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Merck

SAB2501668

Sigma-Aldrich

Anti-UCHL1 (C-terminal) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

别名:

PARK5, PGP9.5, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

goat

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

canine, bovine, rat, rabbit, pig, human

技術

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... UCHL1(7345)

一般說明

Ubiquitin C-terminal hydrolase L1 (UCHL1) is a deubiquitinase which is part of the ubiquitin proteasome system (UPS). The protein is expressed in the nervous system and gonads. The gene encoding UCHL1 is localized on human chromosome 4p13.

免疫原

Peptide with sequence EVRFSAVALCK, from the C-terminal region of the protein sequence according toNP_004172.2

生化/生理作用

Ubiquitin C-terminal hydrolase L1 (UCHL1) has a role in epithelial-mesenchymal transition. It also has roles in invasion and in the cell cycle. UCHL1 catalyzes the hydrolysis of carboxy-terminal ubiquitin esters and amides. The protein has been associated with various cancers.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Ubiquitin carboxyl-terminal esterase L1 (UCHL1) is associated with stem-like cancer cell functions in pediatric high-grade glioma.
Sanchez-diaz PC
PLoS ONE (2017)
UCH-LI acts as a novel prognostic biomarker in gastric cardiac adenocarcinoma.
YAng H
International Journal of Clinical and Experimental Pathology (2015)

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