SAB2500328

Anti-DPP4/CD26 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• 别名: Anti-ADABP, Anti-ADCP2, Anti-Adenosine deaminase complexing protein 2, Anti-CD26, Anti-Dipeptidyl-peptidase 4
• MDL编号: MFCD01094453
• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: goat
• 质量水平: 100
• 偶联物: unconjugated
• 抗体形式: affinity isolated antibody
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 种属反应性: human, mouse, rat, canine
• 技术: flow cytometry: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProt登记号: P27487
• 运输: dry ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... DPP4(1803)

说明

一般描述

Dipeptidyl peptidase 4 (DPP4), also known as cluster of differentiation 26 (CD26), is localized on T- cell surface and interacts with adenosine deaminase (ADA), collagen and CD459. The gene encoding this protein is localized on human chromosome 2q24.2.

免疫原

Peptide with sequence C-PPHFDKSKKYP from the internal region of the protein sequence according to NP_001926.2.

生化/生理作用

Dipeptidyl peptidase 4 (DPP4) or CD26 plays a vital role in T cell co-stimulation, cell-to-cell adhesion and in human immunodeficiency virus (HIV) infection. It functions as a serine protease enzyme that catalyzes the cleavage of dipeptides from peptides containing proline or alanine residues. This protein is a biomarker and therapeutic target for asthma. Deletion of the DPP4 gene affects carbohydrate metabolism which in turn leads to mental retardation and hypotonia. Abnormal expression of the protein is observed during liver regeneration, cirrhosis and liver tumorigenesis. Also, DPP4 level is reduced in serum of chronic obstructive pulmonary disease (COPD) patients.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 2
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable