SAB2107968

Anti-KLHL3 antibody produced in rabbit

IgG fraction of antiserum

• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: rabbit
• 质量水平: 100
• 偶联物: unconjugated
• 抗体形式: IgG fraction of antiserum
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 分子量: 65kDa
• 种属反应性: human, rabbit
• 浓度: 0.5 mg - 1 mg/mL
• 技术: immunoblotting: suitable
• NCBI登记号: NM_017415
• UniProt登记号: Q9UH77
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... KLHL3(26249)

说明

免疫原

Synthetic peptide directed towards the N terminal region of human KLHL3

生化/生理作用

KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77% similarity with Drosophila kelch and 89% similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q; however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.

序列

Synthetic peptide located within the following region: MEGESVKLSSQTLIQAGDDEKNQRTITVNPAHMGKAFKVMNELRSKQLLC

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable