SAB1407707

Anti-ACOT13 antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

• 别名: HT012, MGC4961, PNAS-27
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: mouse
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen ~15 kDa
• 物種活性: human
• 技術: western blot: 1 μg/mL
• NCBI登錄號: NM_018473.2
• UniProt登錄號: Q9NPJ3
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... ACOT13(55856)

说明

一般說明

This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene

免疫原

ACOT13 (NP_060943.1, 1 a.a. ~ 140 a.a) full-length human protein.

Sequence
MTSMTQSLREVIKAMTKARNFERVLGKITLVSAAPGKVICEMKVEEEHTNAIGTLHGGLTATLVDNISTMALLCTERGAPGVSVDMNITYMSPAKLGEDIVITAHVLKQGKTLAFTSVDLTNKATGKLIAQGRHTKHLGN

應用

Anti-ACOT13 antibody produced in mouse is suitable for western blot anaysis.

生化／生理作用

ACOT13 (Acyl-CoA thioesterase 13) is highly involved in the regulation of hepatic lipid and glucose homeostasis. It maintains the intracellular concentration of hepatic free fatty acids (FFAs) and fatty acyl-CoAs under physiological conditions by forming a complex with phosphatidylcholine transfer protein (PC-TP). In liver, it controls the β-oxidation of fatty acids, which is highly crucial for entry of fatty acyl-CoAs into mitochondria.

外觀

Solution in phosphate buffered saline, pH 7.4

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable