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Merck

S3255

Sigma-Aldrich

柄曲霉素

powder, ≥98% (TLC)

别名:

3a,12c-二氢-8-羟基-6-甲氧基-7H-糠醛[3′,2′:4,5]呋[2,3-c]-呫吨-7-酮

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About This Item

经验公式(希尔记法):
C18H12O6
CAS号:
分子量:
324.28
Beilstein:
53259
EC 号:
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.25
价格与库存信息目前不能提供

质量水平

方案

≥98% (TLC)

表单

powder

颜色

yellow

储存温度

−20°C

SMILES字符串

COc1cc2OC3OC=CC3c2c4Oc5cccc(O)c5C(=O)c14

InChI

1S/C18H12O6/c1-21-11-7-12-13(8-5-6-22-18(8)24-12)17-15(11)16(20)14-9(19)3-2-4-10(14)23-17/h2-8,18-19H,1H3

InChI key

UTSVPXMQSFGQTM-UHFFFAOYSA-N

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生化/生理作用

在试验条件下可诱发肺和肝脏肿瘤。

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险声明

预防措施声明

危险分类

Acute Tox. 3 Oral - Carc. 2

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Motoyuki Shimizu et al.
Molecular and cellular biology, 32(18), 3743-3755 (2012-07-18)
Cellular levels of NAD(+) and NADH are thought to be controlled by de novo and salvage mechanisms, although evidence has not yet indicated that they are regulated by NAD(+) degradation. Here we show that the conserved nudix hydrolase isozyme NdxA
Christian Rank et al.
Fungal biology, 115(4-5), 406-420 (2011-05-03)
During the last 50y, the carcinogenic mycotoxin sterigmatocystin (ST) has been reported in several phylogenetically and phenotypically different genera: Aschersonia, Aspergillus, Bipolaris, Botryotrichum, Chaetomium, Emericella, Eurotium, Farrowia, Fusarium, Humicola, Moelleriella, Monocillium and Podospora. We have reexamined all available strains of
Wen-Bing Yin et al.
Molecular microbiology, 83(5), 1024-1034 (2012-01-31)
The eukaryotic bZIP transcription factors are critical players in organismal response to environmental challenges. In fungi, the production of secondary metabolites (SMs) is hypothesized as one of the responses to environmental insults, e.g. attack by fungivorous insects, yet little data
Vellaisamy Ramamoorthy et al.
Molecular microbiology, 85(4), 795-814 (2012-07-13)
In Aspergillus nidulans the global regulatory gene veA is necessary for the biosynthesis of several secondary metabolites, including the mycotoxin sterigmatocystin (ST). In order to identify additional veA-dependent genetic elements involved in regulating ST production, we performed a mutagenesis on
Aleksandrs Versilovskis et al.
Molecular nutrition & food research, 54(1), 136-147 (2009-12-10)
Sterigmatocystin (STC) is a mycotoxin produced by fungi of many different Aspergillus species. Other species such as Bipolaris, Chaetomium, Emiricella are also able to produce STC. STC producing fungi were frequently isolated from different foodstuffs, while STC was regularly detected

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Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.

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