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方案
≥98% (HPLC)
表单
solid
颜色
white
mp
190-191 °C (lit.)
溶解性
DMSO: soluble 10 mg/mL
H2O: insoluble
SMILES字符串
CC(=O)NNC(=O)N1Cc2ccccc2Oc3ccc(Cl)cc13
InChI
1S/C16H14ClN3O3/c1-10(21)18-19-16(22)20-9-11-4-2-3-5-14(11)23-15-7-6-12(17)8-13(15)20/h2-8H,9H2,1H3,(H,18,21)(H,19,22)
InChI key
KNURFLJTOUGOOQ-UHFFFAOYSA-N
基因信息
human ... PTGER1(5731)
rat ... Ptger1(25637)
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
S Santangelo et al.
The Journal of trauma, 48(5), 826-830 (2000-05-24)
Although prostaglandin E2 (PGE2) has been shown to be immunosuppressive, its role in the development of specific bone marrow myeloid lineages after thermal injury and sepsis has yet to be elucidated. The purpose of this study was to demonstrate that
K Oka et al.
The American journal of physiology, 275(6 Pt 2), R1762-R1765 (1998-12-09)
We have previously reported that central injection of PGE2 induces hyperthermia through its actions on EP1 receptors in rats. Because the increase in local synthesis of PGE2 is assumed to be a necessary process in a fever caused by central
L Walch et al.
British journal of pharmacology, 134(8), 1671-1678 (2001-12-12)
1. To characterize the prostanoid receptors (TP, FP, EP(1) and/or EP(3)) involved in the vasoconstriction of human pulmonary veins, isolated venous preparations were challenged with different prostanoid-receptor agonists in the absence or presence of selective antagonists. 2. The stable thromboxane
J B Farmer et al.
British journal of pharmacology, 52(4), 559-565 (1974-12-01)
1 The effects of the prostaglandin synthetase inhibitor, indomethacin and the prostaglandin antagonist SC-19220 (1-acetyl-2-[8-chloro-10,11-dihydrodibenz (b,f) (1,4)oxazepine-10-carbonyl] hydrazine), were examined on the tone of the guinea-pig isolated tracheal preparation and on the responses of the preparation to prostaglandin F(2alpha), arachidonic
K Fushimi et al.
Osteoarthritis and cartilage, 12(11), 895-903 (2004-10-27)
Calpains are known as Ca(2+)-dependent intracellular neutral cysteine proteases. However, m-calpain is detected in synovial fluid of arthritic joints and is shown to possess the proteoglycanase activity in vitro. The mechanism of m-calpain release into the extracellular spaces during arthritis
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