RAB1320

人组织蛋白酶Z ELISA

for serum, plasma and cell culture supernatants

• UNSPSC代码: 12352200

属性

• 种属反应性: human
• 技术: ELISA: suitable
• 输入: sample type serum; sample type plasma; sample type cell culture supernatant(s)
• assay range: inter-assay cv: <12%; intra-assay cv: <10%
• 运输: wet ice
• 储存温度: −20°C
• 基因信息: human ... CTSZ(1522)

说明

一般描述

Cathepsins are normally localized in lysosomes of almost all mammalian cells, but under certain conditions they can be secreted from the cells that take part in local proteolysis.[1][2] Cathepsin Z is a cysteine protease, predominantly expressed in immune cells including monocytes, macrophages or dendritic cells.[3][4][5]

This ELISA antibody pair detects Human Cathepsin Z (CTSZ/Cathepsin X/Cathepsin P)

应用

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

生化/生理作用

Cathepsins are lysosomal proteases that play an important role in the intracellular degradation of exogenous and endogenous proteins, activation of enzyme precursors, and tumor invasion and metastasis.[6] Cathepsin Z is known to be associated with the pathogenesis of cancer and promotes the development and proliferation of tumor cells. Cathepsin Z mediates the process of proliferation, migration, maturation, adhesion, signal transduction and phagocytosis of immune cells.[3][4][5]

其他说明

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

安全信息

• 象形图: GHS05
• 警示用语：: Warning
• 危险声明: H290
• 预防措施声明: P234 - P390
• 危险分类: Met. Corr. 1
• 储存分类代码: 8A - Combustible corrosive hazardous materials
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable