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物種活性
mouse
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
capture ELISA: suitable
輸入
sample type cell lysate
sample type tissue lysate
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1 pg/mL
standard curve range: 0.819-200 pg/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
mouse ... Il4(16189)
一般說明
The Mouse IL-4 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse IL-4 in cell lysate and tissue lysate.
免疫原
Recombinant Mouse IL-4
應用
For research use only. Not for use in diagnostic procedures.
Mouse IL-4 ELISA kit has been used for determining the levels of IL-4 in serum sample.[1]
Mouse IL-4 ELISA kit has been used for determining the levels of IL-4 in serum sample.[1]
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
生化／生理作用
IL-4 (interleukin 4) is a pleiotropic cytokine.[2] It regulates diverse T and B cell responses including cell proliferation, survival and gene expression.[3] IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 (T helper) cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response.[3] Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 (immunoglobulin G1) and IgE isotypes.[4] Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy.[5] IL-4 helps in long-term recovery after cerebral ischemia by controlling the activities of microglia/macrophage.[6] In mice, absence of IL-4 is associated with a state anxiety-like behavior.[7]
其他說明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
试剂盒组分也可单独购买
产品编号
说明
化学品安全说明书
- RABDIL6ELISA 5X Sample Diluent Buffer (Item D2)化学品安全说明书
- RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)化学品安全说明书
- RABLYSIS12X Cell Lysis Buffer (Item J)化学品安全说明书
- RABSTOP3ELISA Stop Solution (Item I)化学品安全说明书
- RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)化学品安全说明书
- RABWASH420X Wash Buffer (Item B)化学品安全说明书
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8B - Non-combustible corrosive hazardous materials
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Flavonoid Glycosides of Polygonum capitatum protect against inflammation associated with Helicobacter pylori infection.
Zhang Shu
PLoS ONE, 10(5) (2015)
Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells.
Rincon M
The Journal of Experimental Medicine, 185, 461-469 (1997)
Ile50Val variant of IL4R alpha upregulates IgE synthesis and associates with atopic asthma.
Mitsuyasu H
Nature Genetics, 19, 119-120 (1998)
IL-4 Knock Out Mice Display Anxiety-Like Behavior.
Moon ML
Behavior Genetics, 45, 451-460 (2015)
Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the Fc epsilonRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells.
Pawankar R
The Journal of Clinical Investigation, 99, 1492-1492 (1997)
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