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Merck

RAB0278

Sigma-Aldrich

Rat IL-1 β ELISA Kit

for cell and tissue lysates

别名:

Il-1 beta, Interleukin-1 beta

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About This Item

分類程式碼代碼:
41116158
NACRES:
NA.32

物種活性

rat

包裝

kit of 96 wells (12 strips x 8 wells)

技術

ELISA: suitable
capture ELISA: suitable

輸入

sample type cell lysate
sample type tissue lysate

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/mL
standard curve range: 68.59-50000 pg/mL

檢測方法

colorimetric

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

rat ... Il1b(24494)

一般說明

The Rat IL-1 β ELSA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Rat IL-1β cell lysate and tissue lysate.

免疫原

Recombinant Rat IL-1 β

應用

For research use only. Not for use in diagnostic procedures

Rat IL-1 Β ELISA Kit has been used to measure IL-1 Β levels .
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

生化/生理作用

Pro-inflammatory cytokine IL-1 Β (IL1B), which is highly expressed on Β-adrenoreceptor in obese adipose tissues, is implicated in induction of uncoupling protein 1 (UCP1) expression via extracellular signal-regulated kinase (ERK) activation in adipocytes. Macrophage autophagy inhibits the production of inflammasome-dependent IL-1Β and thereby it plays a vital role in reducing acute toxin-induced liver injury and death. In rats, IL-1Β enhanced neurogenesis and plasticity of carotid bodies (CB) by triggering ERK1/2 activation. IL-1Β plays a vital role in alteration of glomerular hemodynamics via stimulating the production of prostaglandin E2 (PGE2) in the mesangial cells.

其他說明

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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产品编号
说明
化学品安全说明书

  • RABDIL6ELISA 5X Sample Diluent Buffer (Item D2)化学品安全说明书

  • RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)化学品安全说明书

  • RABLYSIS12X Cell Lysis Buffer (Item J)化学品安全说明书

  • RABSTOP3ELISA Stop Solution (Item I)化学品安全说明书

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)化学品安全说明书

  • RABWASH420X Wash Buffer (Item B)化学品安全说明书

象形圖

Corrosion

訊號詞

Warning

危險聲明

防範說明

危險分類

Met. Corr. 1

儲存類別代碼

8A - Combustible corrosive hazardous materials


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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访问文档库

Interleukin-1? promotes the neurogenesis of carotid bodies by stimulating the activation of ERK1/2.
Xue F
Respiratory Physiology & Neurobiology null
Diosmin Modulates the NF-kB Signal Transduction Pathways and Downregulation of Various Oxidative Stress Markers in Alloxan-Induced Diabetic Nephropathy.
Ahmed S
Inflammation null
Macrophage autophagy limits acute toxic liver injury in mice through down regulation of interleukin-1?.
Ilyas G
Journal of Hepatology null
Proinflammatory cytokine interleukin-1? suppresses cold-induced thermogenesis in adipocytes.
Goto T
Cytokine null
Ashraf Al-Brakati et al.
International journal of nanomedicine, 16, 4335-4349 (2021-07-09)
Selenium nanoparticles (SeNPs) have recently gained much attention in nanomedicine applications owing to their unique biological properties. Biosynthesis of SeNPs using nutraceuticals as lycopene (LYC) maximizes their stability and bioactivities. In this context, this study aimed to elucidate the renoprotective

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