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RAB0220

Sigma-Aldrich

小鼠 ICAM-1 ELISA 试剂盒

for serum, plasma and cell culture supernatant

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About This Item

分類程式碼代碼:
41116158
NACRES:
NA.32

$858.00


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物種活性

mouse

包裝

kit of 96 wells (12 strips x 8 wells)

技術

ELISA: suitable
capture ELISA: suitable

輸入

sample type serum
sample type plasma
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 20 pg/mL
standard curve range: 24.69-6000 pg/mL

檢測方法

colorimetric

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

mouse ... Icam1(15894)

一般說明

The Mouse ICAM-1 (Intercellular Adhesion Molecule-1) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of mouse ICAM-1 in serum, plasma, cell culture supernatants and urine.

免疫原

Recombinant Mouse ICAM1

應用

请参考Protocol了解详情。

生化/生理作用

Intercellular adhesion molecule-1 (ICAM-1) is a member of immunoglobulin (Ig) superfamily. It is an inducible transmembrane glycoprotein. ICAM-1 mediates adhesion of circulating leukocytes to the endothelial membrane and blood vessel.[1][2] ICAM-1 might cause atherosclerosis and the polymorphism in ICAM-1 has reduced risk to cardiovascular diseases.[1] IL-6 induces the upregulation of ICAM-1 and leads to metastasis of osteosarcoma cells.[2] ICAM-1 causes invasion and metastasis of breast cancer cells.[3] ICAM-1 is an important receptor for rhinovirus and Haemophilus influenzae binding. Upregulation of ICAM-1 in the respiratory tract of chronic airway limitation patients increases the risk of respiratory infections.[4]

其他說明

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

试剂盒组分也可单独购买

产品编号
说明
化学品安全说明书

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)化学品安全说明书

  • RABELADDELISA 5X Assay/Sample Diluent Buffer D (Item K)化学品安全说明书

  • RABSTOP3ELISA Stop Solution (Item I)化学品安全说明书

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)化学品安全说明书

  • RABWASH420X Wash Buffer (Item B)化学品安全说明书

象形圖

Corrosion

訊號詞

Warning

危險聲明

防範說明

危險分類

Met. Corr. 1

儲存類別代碼

8A - Combustible corrosive hazardous materials


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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ICAM-1 gene rs5498 polymorphism decreases the risk of coronary artery disease
Liu A, et al.
Medicine, 97(40), e12523-e12523 (2018)
The main rhinovirus respiratory tract adhesion site (ICAM-1) is upregulated in smokers and patients with chronic airflow limitation (CAL)
Shukla SD, et al.
Respiratory Research, 18(1), 6-6 (2017)
IL-6 promotes ICAM-1 expression and cell motility in human osteosarcoma
Lin YM, et al.
Cancer Letters, 328(1), 135-143 (2013)
Role of ICAM1 in invasion of human breast cancer cells
Rosette C, et al.
Carcinogenesis, 26(5), 943-950 (2005)
Heather D Moore et al.
Radiation research, 181(5), 521-530 (2014-04-12)
In the event of a nuclear incident in a heavily populated area, the surge in demand for medical evaluation will likely overwhelm our emergency care system, compromising our ability to care for victims with life-threatening injuries or exposures. Therefore, there

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