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物種活性
human
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
capture ELISA: suitable
輸入
sample type urine
sample type serum
sample type cell culture supernatant(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 20 pg/mL
standard curve range: 20.58-15000 pg/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... CEACAM1(634)
一般說明
The Human CEACAM-1 (Carcinoembryonic Antigen- related Cell Adhesion Molecule 1) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human CEACAM-1 in serum, plasma, cell culture supernatants and urine.
Serum carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is a transmembrane glycoprotein and is localized to endothelial, epithelial, lymphoid and myeloid cells.[1]The CEACAM-1 gene is mapped to human chromosome 19q13.2.[2]
Serum carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is a transmembrane glycoprotein and is localized to endothelial, epithelial, lymphoid and myeloid cells.[1]The CEACAM-1 gene is mapped to human chromosome 19q13.2.[2]
免疫原
Recombinant Human CEACAM1
應用
请参考Protocol了解详情。
生化／生理作用
Serum carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) participates in cell adhesion mechanism through homophilic or heterophilic interactions.[3] Abnormal expression of the CEACAM1 gene is observed in a number of tumors.[4] Ceacam1 possesses tyrosine phosphatase, an inhibitory motif, via which the receptor activates its inhibitory signals.[5]
其他說明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
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产品编号
说明
化学品安全说明书
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
CEACAM1: contact-dependent control of immunity.
Gray-Owen S D and Blumberg R S
Nature Reviews: Immunology, 6(6), 433-433 (2006)
Up-regulation of carcinoembryonic antigen-related cell adhesion molecule 1 in gastrointestinal cancer and its clinical relevance.
Zhou M, et al.
Acta biochimica et biophysica Sinica, 49(8), 737-743 (2017)
Rong Zhang et al.
Journal of ethnopharmacology, 155(1), 104-112 (2014-05-03)
The present study systematically investigate the in vivo and in vitro effect of total lignans (TL) extracted from Eucommia ulmoides Oliv. barks on bone formation using ovariectomy rat model and primary cultures of rat osteoblasts. Eighty 3-month-old female Sprague-Dawley rats
SOX9 indirectly regulates CEACAM1 expression and immune resistance in melanoma cells.
Ashkenazi S, et al.
Oncotarget, 7(21), 30166-30166 (2016)
Suppression of human metapneumovirus (HMPV) infection by the innate sensing gene CEACAM1.
Diab M, et al.
Oncotarget, 7(41), 66468-66468 (2016)
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